Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FRMD4A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FRMD4A |
| Key Genes/Proteins | p53, EWSR1, RNA, P53, AND, PKM2 |
| Related Diseases | Als, Cancer, Tumor, ALS |
graph TD
FRMD4A["FRMD4A"]
FRMD4A -->|"expressed in"| Circfrmd4A["Circfrmd4A"]
FRMD4A -->|"inhibits"| Als["Als"]
FRMD4A -->|"activates"| Cancer["Cancer"]
FRMD4A -->|"activates"| Tumor["Tumor"]
FRMD4A -->|"inhibits"| ALS["ALS"]
FRMD4A -->|"activates"| EWSR1["EWSR1"]
FRMD4A -->|"activates"| RNA["RNA"]
FRMD4A -->|"activates"| P53["P53"]
p53["p53"] -->|"upregulates"| FRMD4A
P53 -->|"activates"| FRMD4A
RNA -->|"activates"| FRMD4A
AND["AND"] -->|"activates"| FRMD4A
CANCER["CANCER"] -->|"activates"| FRMD4A
EWSR1 -->|"activates"| FRMD4A
PKM2["PKM2"] -->|"inhibits"| FRMD4A| Target | Relation | Type | Str |
|---|---|---|---|
| Circfrmd4A | expressed_in | compound | 0.90 |
| Als | inhibits | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| Tumor | activates | disease | 0.65 |
| ALS | inhibits | disease | 0.65 |
| EWSR1 | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| P53 | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| RNA | encodes | gene | 0.60 |
| PKM2 | inhibits | gene | 0.60 |
| Rb | inhibits | protein | 0.60 |
| Raf | activates | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||