Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DRAK2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | DRAK2 |
| Key Genes/Proteins | SRSF6, RNA, AND, SRPK1, APOPTOSIS |
| Related Diseases | Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease Progression, NAFLD, NASH, hepatic lipid accumulation |
graph TD
DRAK2["DRAK2"]
DRAK2 -->|"causes"| Nonalcoholic_Fatty_Liver_Disea["Nonalcoholic Fatty Liver Disease Progression"]
DRAK2 -->|"modulates"| RNA_Alternative_Splicing["RNA Alternative Splicing"]
DRAK2 -->|"interacts"| SRSF6["SRSF6"]
DRAK2 -->|"inhibits"| SRPK1["SRPK1"]
DRAK2 -->|"activates"| APOPTOSIS["APOPTOSIS"]
DRAK2 -->|"activates"| Apoptosis["Apoptosis"]
DRAK2 -->|"target for"| Ngf["Ngf"]
DRAK2 -->|"target for"| App["App"]
GENES["GENES"] -->|"inhibits"| DRAK2
SRPK1 -->|"inhibits"| DRAK2| Target | Relation | Type | Str |
|---|---|---|---|
| Nonalcoholic Fatty Liver Disease | associated_with | disease | 0.95 |
| Nonalcoholic Fatty Liver Disease Progression | causes | phenotype | 0.90 |
| NAFLD | aggravates | disease | 0.90 |
| NASH | aggravates | disease | 0.90 |
| RNA Alternative Splicing | modulates | process | 0.88 |
| SRSF6 | interacts_with | protein | 0.85 |
| hepatic lipid accumulation | promotes | phenotype | 0.80 |
| SRSF6 | binds | protein | 0.80 |
| Nonalcoholic Steatohepatitis | promotes | disease | 0.80 |
| APOPTOSIS | aggravates | process | 0.70 |
| Hepatitis | associated_with | disease | 0.65 |
| RNA | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| SRPK1 | inhibits | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| Apoptosis | activates | pathway | 0.60 |
| Ngf | therapeutic_target | protein | 0.60 |
| App | therapeutic_target | protein | 0.60 |
| RNA | interacts_with | gene | 0.60 |
| apoptosis pathway | participates_in | pathway | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||