protein

DRD4PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DRD4PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

Summary

Drd4 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	DRD4PROTEIN
Protein Type	Receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	prefrontal cortex, hippocampus, and hypothalamus, where it modulates cognitive functions, atten
Subcellular Localization	** \| Plasma membrane, dendritic spines \|
Molecular Weight	55 kDa
GeneCards	DRD4PROTEIN
Human Protein Atlas	DRD4PROTEIN
Alternative splicing	Produces multiple isoforms with differential signaling properties
N-linked glycosylation sites	Located in the N-terminus for proper protein folding
Attention and cognition	Prefrontal cortex expression modulates working memory and attentional processes
Impulse control	Striatal and cortical expression influences response inhibition
Reward processing	Limbic system involvement in novelty-seeking and reward anticipation
Hormonal regulation	Hypothalamic expression modulates pituitary hormone release
Associated Diseases	Addiction, Opioid, SUD
Interactions	DRD2, OPRM1, NEURON, PARKINSON, PARKINSON'S DISEASE, BDNF
KG Connections	75 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

drd4 Protein

protein · 580 words

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Pathway Diagram

graph TD
    DRD4PROTEIN["DRD4PROTEIN"]
    neurodegeneration["neurodegeneration"]
    DRD4PROTEIN -->|"implicated_in"| neurodegeneration
    style DRD4PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found