protein

HSP110

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HSP110: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections
0Hypotheses
0Analyses
11Outgoing
4Incoming

Summary

Page for Hsp110 Protein

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🔬 Protein Info
Gene SymbolHSP110
Molecular Weight94 kDa
GeneCardsHSP110
Human Protein AtlasHSP110
InteractionsHSP40, HSP70, HSPA1A, HSPA8, HSPH1, RNA
KG Connections15 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Amyloid-beta Fibril Formation Pathway

mechanism · 3761 words

Proteostasis Network Dysfunction Comparison Across Neurodegenerative Diseases

mechanism · 3519 words

SOD1 Superoxide Dismutase 1 ALS Causal Chain

mechanism · 3026 words

DNAJB5 (DnaJ Heat Shock Protein Family Member B5)

gene · 2425 words

Pathway Diagram

graph TD
    HSP110["HSP110"]
    HSP40["HSP40"]
    HSP110 -->|"activates"| HSP40
    HSP70["HSP70"]
    HSP110 -->|"activates"| HSP70
    HSPA1A["HSPA1A"]
    HSP110 -->|"activates"| HSPA1A
    HSPA8["HSPA8"]
    HSP110 -->|"activates"| HSPA8
    HSPH1["HSPH1"]
    HSP110 -->|"activates"| HSPH1
    HSP110 -->|"interacts with"| HSP40
    HSP110 -->|"interacts with"| HSP70
    RNA["RNA"]
    HSP110 -->|"interacts with"| RNA
    TDP_43["TDP-43"]
    HSP110 -->|"interacts with"| TDP_43
    DNAJA1["DNAJA1"]
    DNAJA1 -->|"activates"| HSP110
    DNAJB1["DNAJB1"]
    DNAJB1 -->|"activates"| HSP110
    HSC70["HSC70"]
    HSC70 -->|"activates"| HSP110
    ATP["ATP"]
    ATP -->|"interacts with"| HSP110
    style HSP110 fill:#0d47a1,stroke:#42a5f5,stroke-width:2px,color:#fff

Outgoing (12)

TargetRelationTypeStr
Proteostasisregulatesprocess0.90
HSP40regulatesgene0.60
HSP40activatesgene0.55
HSP70activatesgene0.55
HSPA1Aactivatesgene0.55

Incoming (4)

SourceRelationTypeStr
DNAJA1activatesgene0.55
DNAJB1activatesgene0.55
HSC70activatesgene0.55
ATPinteracts_withgene0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found