Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HSP110: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | HSP110 |
| Molecular Weight | 94 kDa |
| GeneCards | HSP110 |
| Human Protein Atlas | HSP110 |
| Interactions | HSP40, HSP70, HSPA1A, HSPA8, HSPH1, RNA |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HSP110["HSP110"]
HSP40["HSP40"]
HSP110 -->|"activates"| HSP40
HSP70["HSP70"]
HSP110 -->|"activates"| HSP70
HSPA1A["HSPA1A"]
HSP110 -->|"activates"| HSPA1A
HSPA8["HSPA8"]
HSP110 -->|"activates"| HSPA8
HSPH1["HSPH1"]
HSP110 -->|"activates"| HSPH1
HSP110 -->|"interacts with"| HSP40
HSP110 -->|"interacts with"| HSP70
RNA["RNA"]
HSP110 -->|"interacts with"| RNA
TDP_43["TDP-43"]
HSP110 -->|"interacts with"| TDP_43
DNAJA1["DNAJA1"]
DNAJA1 -->|"activates"| HSP110
DNAJB1["DNAJB1"]
DNAJB1 -->|"activates"| HSP110
HSC70["HSC70"]
HSC70 -->|"activates"| HSP110
ATP["ATP"]
ATP -->|"interacts with"| HSP110
style HSP110 fill:#0d47a1,stroke:#42a5f5,stroke-width:2px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| Proteostasis | regulates | process | 0.90 |
| HSP40 | regulates | gene | 0.60 |
| HSP40 | activates | gene | 0.55 |
| HSP70 | activates | gene | 0.55 |
| HSPA1A | activates | gene | 0.55 |
| HSPA8 | activates | gene | 0.55 |
| HSPH1 | activates | gene | 0.55 |
| HSP40 | interacts_with | gene | 0.55 |
| HSP70 | interacts_with | gene | 0.55 |
| RNA | interacts_with | gene | 0.55 |
| TDP-43 | interacts_with | gene | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||