concept

ITGB6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ITGB6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections

0Hypotheses

0Analyses

22Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	ITGB6
Key Genes/Proteins	STAT3, KRAS, HER3, AND, MEK, PRMT5
Related Diseases	Tacrolimus-Induced Chronic Nephrotoxicity, Tubular Injury, Non-Small Cell Lung Cancer, Als, Cancer

Pathway Diagram

graph TD
    ITGB6["ITGB6"]
    ITGB6 -->|"target for"| Als["Als"]
    ITGB6 -->|"target for"| Cancer["Cancer"]
    ITGB6 -->|"interacts"| ALS["ALS"]
    ITGB6 -->|"target for"| KRAS["KRAS"]
    ITGB6 -->|"causes"| HER3["HER3"]
    ITGB6 -->|"causes"| AND["AND"]
    ITGB6 -->|"causes"| MEK["MEK"]
    HER3 -->|"target for"| ITGB6
    PRMT5["PRMT5"] -->|"target for"| ITGB6
    MEK -->|"causes"| ITGB6
    CANCER["CANCER"] -->|"interacts"| ITGB6
    KRAS -->|"target for"| ITGB6

Outgoing (22)

Target	Relation	Type	Str
Tacrolimus-Induced Chronic Nephrotoxicity	implicated_in	disease	0.90
Renal Fibrogenesis	associated_with	process	0.85
Tubular Injury	associated_with	phenotype	0.85
Non-Small Cell Lung Cancer	associated_with	disease	0.80
STAT3	therapeutic_target	gene	0.80
Als	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Cancer	interacts_with	disease	0.65
ALS	interacts_with	disease	0.65
KRAS	therapeutic_target	gene	0.60
HER3	causes	gene	0.60
AND	causes	gene	0.60
MEK	causes	gene	0.60
PRMT5	causes	gene	0.60
RAF	causes	gene	0.60
CANCER	interacts_with	gene	0.60
KRAS	causes	gene	0.60
HER3	therapeutic_target	gene	0.60
PRMT5	therapeutic_target	gene	0.60
Raf	therapeutic_target	protein	0.60
Mek	therapeutic_target	protein	0.60
Ras	therapeutic_target	protein	0.60

Incoming (7)

Source	Relation	Type	Str
STAT3	regulates	gene	0.85
HER3	therapeutic_target	gene	0.60
PRMT5	therapeutic_target	gene	0.60
MEK	causes	gene	0.60
HER3	causes	gene	0.60
CANCER	interacts_with	gene	0.60
KRAS	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found