protein

LAMP5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LAMP5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections
0Hypotheses
0Analyses
16Outgoing
8Incoming
0Experiments

Summary

Page for LAMP5 Protein

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🔬 Protein Info
Gene SymbolLAMP5
Full NameLAMP5 — Lysosomal Associated Membrane Protein 5
AliasesLysosomal Associated Membrane Protein 5
Chromosome20p13.
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionneurons and has been implicated in Alzheimer's disease susceptibility through genome-wide association studies
Molecular Weight45 kDa
Amino Acids299 aa
Pathwaysoxidative stress response
NCBI Gene IDSearch NCBI
GeneCardsLAMP5
Human Protein AtlasLAMP5
Associated DiseasesALS, Alzheimer
KG Connections24 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (12)

Knowledge base pages for this entity

Canonical Page

LAMP5 Gene — Lysosomal Associated Membrane Protein 5

gene · 591 words

Cortical Ivy Cells

cell · 2948 words

Interneurons — Cell Type Hierarchy

cell · 2170 words

Cortical Pyramidal Neurons (Layers 2/3)

cell · 1519 words

Hippocampal Ivy Cells

cell · 1312 words

Neurogliaform Cells

cell · 1146 words

Pathway Diagram

flowchart TD
    N0["LAMP5"]
    N1["Alzheimer"]
    N0 -->|"expressed in"| N1
    N2["Als"]
    N0 -->|"expressed in"| N2
    N3["ALS"]
    N0 -->|"expressed in"| N3
    N4["SST"]
    N0 -->|"associated with"| N4
    N5["Neuron"]
    N0 -->|"associated with"| N5
    N6["PVALB"]
    N0 -->|"associated with"| N6
    N7["ALZHEIMER"]
    N7 -->|"expressed in"| N0
    N8["RNA"]
    N8 -->|"expressed in"| N0
    N6 -->|"associated with"| N0
    N9["NEURON"]
    N9 -->|"associated with"| N0
    N10["GENES"]
    N10 -->|"expressed in"| N0
    N4 -->|"associated with"| N0
    N11["AND"]
    N11 -->|"associated with"| N0
    N12["ALZHEIMER'S DISEASE"]
    N12 -->|"expressed in"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N4 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene
    class N10 gene
    class N11 gene
    class N12 gene

Outgoing (16)

TargetRelationTypeStr
Alzheimerexpressed_indisease0.65
Alsexpressed_indisease0.65
ALSexpressed_indisease0.65
SSTassociated_withgene0.60
PVALBassociated_withgene0.60

Incoming (8)

SourceRelationTypeStr
PVALBassociated_withgene0.60
SSTassociated_withgene0.60
ALZHEIMERexpressed_ingene0.60
RNAexpressed_ingene0.60
NEURONassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found