Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LNK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| CBL | interacts_with | protein | 0.95 |
| Dopaminergic Neurodegeneration | regulates | process | 0.95 |
| Dopaminergic neuron vulnerability | mediates | phenotype | 0.91 |
| HNRNPA2B1 | regulates | protein | 0.90 |
| Parkinson Disease | associated_with | disease | 0.90 |
| Dopaminergic Neurons | regulates | cell_type | 0.90 |
| Ferroptosis | exacerbates | process | 0.89 |
| dopaminergic neuron vulnerability | contributes_to | phenotype | 0.88 |
| Parkinson's disease | associated_with | disease | 0.88 |
| Hnrnpa2B1 | promotes | protein | 0.85 |
| dopaminergic neuron | causes | cell_type | 0.85 |
| therapeutic_target | involved_in | phenotype | 0.85 |
| Motor Impairment | correlates_with | phenotype | 0.85 |
| Parkinson's Disease | risk_factor_for | disease | 0.85 |
| motor impairment | associated_with | phenotype | 0.80 |
| neurodegeneration | associated_with | disease | 0.60 |
| ferroptosis | participates_in | pathway | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| RNA | activates | gene | 0.60 |
| benchmark_ot_ad_answer_key:LNK | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| lifitegrast | targets | drug | 0.85 |
| Lifitegrast | modulates | drug | 0.85 |
| lifitegrast | binds | drug | 0.75 |
| CBL | activates | gene | 0.60 |
| HNRNPA2B1 | activates | gene | 0.60 |
| CBL | regulates | gene | 0.60 |
| GPX4 | regulates | gene | 0.60 |
| HNRNPA2B1 | regulates | gene | 0.60 |
| benchmark_ot_ad_answer_key:LNK | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||