Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PARKINSON DISEASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | PARKINSON DISEASE |
| Key Genes/Proteins | LRRK2 |
Knowledge base pages for this entity
graph TD
PARKINSON_DISEASE["PARKINSON DISEASE"]
PARKINSON_DISEASE -->|"risk_factor_for"| Dementia["Dementia"]
PARKINSON_DISEASE -->|"causes"| Cognitive_Impairment["Cognitive Impairment"]
Rotenone["Rotenone"] -->|"causes"| PARKINSON_DISEASE
PRKN["PRKN"] -->|"risk_factor_for"| PARKINSON_DISEASE
Mitochondrial_Dysfunction["Mitochondrial Dysfunction"] -->|"contributes to"| PARKINSON_DISEASE
Vinpocetine["Vinpocetine"] -.protects against.-> PARKINSON_DISEASE
Ageing["Ageing"] -->|"risk_factor_for"| PARKINSON_DISEASE
Snca["Snca"] -.biomarker for.-> PARKINSON_DISEASE
GBA["GBA"] -->|"risk_factor_for"| PARKINSON_DISEASE| Target | Relation | Type | Str |
|---|---|---|---|
| Dementia Risk | risk_factor_for | phenotype | 0.95 |
| Dementia | risk_factor_for | disease | 0.95 |
| Dementia | causes | disease | 0.95 |
| Cognitive Impairment | causes | phenotype | 0.92 |
| Cognitive Decline | associated_with | phenotype | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LRRK2 | associated_with | gene | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 14 hypotheses Top: 0.622
neurodegeneration | 2026-04-02 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||