Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MAO-B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MAO-B |
| Key Genes/Proteins | CYP1A1, TAAR1, AHR, CYP1A2, GENES, MAO |
| Related Pathways | Mitochondrial Function |
Knowledge base pages for this entity
graph TD
MAO_B["MAO-B"]
MAO_B -->|"regulates"| CYP1A1["CYP1A1"]
MAO_B -->|"regulates"| TAAR1["TAAR1"]
MAO_B -->|"activates"| AHR["AHR"]
MAO_B -->|"regulates"| CYP1A2["CYP1A2"]
MAO_B -->|"regulates"| Mitochondrial_Function["Mitochondrial Function"]
MAO_B -->|"regulates"| GENES["GENES"]
MAO_B -->|"activates"| MAO["MAO"]
MAO_B -->|"activates"| AND["AND"]
AADC["AADC"] -->|"regulates"| MAO_B
MAO -->|"activates"| MAO_B
ROS["ROS"] -->|"regulates"| MAO_B
CYP1A2 -->|"regulates"| MAO_B
TAAR1 -->|"regulates"| MAO_B
CYP1A1 -->|"regulates"| MAO_B
AHR -->|"activates"| MAO_B
GFAP["GFAP"] -->|"activates"| MAO_B| Target | Relation | Type | Str |
|---|---|---|---|
| CYP1A1 | regulates | gene | 0.60 |
| TAAR1 | regulates | gene | 0.60 |
| AHR | activates | gene | 0.60 |
| CYP1A2 | regulates | gene | 0.60 |
| Mitochondrial Function | regulates | pathway | 0.60 |
| GENES | regulates | gene | 0.60 |
| MAO | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| AADC | regulates | gene | 0.60 |
| Actin | regulates | protein | 0.60 |
| Rb | activates | protein | 0.60 |
| NEUROTOXICITY | activates | process | 0.35 |
| TAU | activates | protein | 0.35 |
| NEUROTOXICITY | implicated_in | process | 0.35 |
| ROS | regulates | protein | 0.35 |
| MICRORNA REGULATION | regulates | process | 0.35 |
| SELEGILINE | inhibits | drug | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity