concept

MAO

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

234Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	MAO-B Inhibitors for Parkinson's Disease — Investment Landscape Analysis
Summary	Page for MAO-B Inhibitors for Parkinson's Disease — Investment Landscape Analysis
Related Diseases	Ms, Parkinson, Neurodegeneration, Alzheimer, Atherosclerosis

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    MAO["MAO"]
    style MAO fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    MAO -->|"catalyzes"| Neurotransmitter_Metabolism["Neurotransmitter Metabolism"]
    MAO -->|"involved_in"| Neurotoxicity["Neurotoxicity"]
    MAO -->|"regulates"| Ms["Ms"]
    MAO -.->|"inhibits"| Atherosclerosis["Atherosclerosis"]
    MAO -.->|"inhibits"| ALS["ALS"]
    MAO -.->|"inhibits"| Tumor["Tumor"]
    MAO -.->|"inhibits"| Cancer["Cancer"]
    MAO -.->|"biomarker for"| Neurodegeneration["Neurodegeneration"]
    MAO -.->|"biomarker for"| Neuroinflammation["Neuroinflammation"]
    MAO -.->|"biomarker for"| Inflammation["Inflammation"]
    GFAP([GFAP]) -->|"contributes to"| MAO
    PER([PER]) -->|"target for"| MAO
    SLC7A11([SLC7A11]) -->|"regulates"| MAO
    ACETYL_COA([ACETYL-COA]) -->|"regulates"| MAO
    GPX4([GPX4]) -->|"regulates"| MAO
    LC3([LC3]) -.->|"inhibits"| MAO
    APOE([APOE]) -.->|"inhibits"| MAO
    EIF4EBP1([EIF4EBP1]) -.->|"inhibits"| MAO
    ABCA1([ABCA1]) -.->|"inhibits"| MAO
    ULK1([ULK1]) -.->|"inhibits"| MAO

Outgoing (147)

Target	Relation	Type	Str
Ms	associated_with	disease	0.65
Parkinson	associated_with	disease	0.65
Neurodegeneration	associated_with	disease	0.65
Alzheimer	associated_with	disease	0.65
Ms	regulates	disease	0.65
Atherosclerosis	inhibits	disease	0.65
ALS	inhibits	disease	0.65
Tumor	inhibits	disease	0.65
Cancer	inhibits	disease	0.65
Neurodegeneration	biomarker_for	disease	0.65
Neuroinflammation	biomarker_for	disease	0.65
Inflammation	biomarker_for	disease	0.65
Als	inhibits	disease	0.65
Ferroptosis	therapeutic_target	disease	0.65
Alzheimer	inhibits	disease	0.65
Neuroinflammation	inhibits	disease	0.65
Parkinson	inhibits	disease	0.65
Depression	inhibits	disease	0.65
Anxiety	inhibits	disease	0.65
Inflammation	inhibits	disease	0.65
TAU	contributes_to	gene	0.65
OXIDATIVE STRESS	regulates	phenotype	0.65
ALZHEIMER	associated_with	gene	0.60
AND	therapeutic_target	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
UBIQUITIN	associated_with	gene	0.60
NEURODEGENERATION	associated_with	gene	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
Mitochondrial Function	associated_with	pathway	0.60
Epigenetic	associated_with	pathway	0.60
Proteasome	associated_with	pathway	0.60
Oxidative Stress	associated_with	pathway	0.60
Ubiquitin-Proteasome	associated_with	pathway	0.60
AUTOPHAGY	regulates	gene	0.60
GPX4/SLC7A11	regulates	gene	0.60
AND	regulates	gene	0.60
FERROPTOSIS	regulates	gene	0.60
NCOA4	regulates	gene	0.60
Autophagy	regulates	pathway	0.60
Ferroptosis	regulates	pathway	0.60
AND	inhibits	gene	0.60
P62	inhibits	gene	0.60
GENES	inhibits	gene	0.60
ABCG1	inhibits	gene	0.60
LDL	inhibits	gene	0.60
P2RY12	inhibits	gene	0.60
MTOR	inhibits	gene	0.60
MAP1LC3	inhibits	gene	0.60
PI3K	inhibits	gene	0.60
Autophagy	inhibits	pathway	0.60

Incoming (87)

Source	Relation	Type	Str
GFAP	contributes_to	gene	0.65
ROS	produces	phenotype	0.65
OXIDATIVE STRESS	associated_with	gene	0.60
PER	therapeutic_target	gene	0.60
PARKINSON	associated_with	gene	0.60
SLC7A11	regulates	gene	0.60
ACETYL-COA	regulates	gene	0.60
GPX4	regulates	gene	0.60
LC3	inhibits	gene	0.60
APOE	inhibits	gene	0.60
EIF4EBP1	inhibits	gene	0.60
ABCA1	inhibits	gene	0.60
ULK1	inhibits	gene	0.60
SQSTM1	inhibits	gene	0.60
APOA1	inhibits	gene	0.60
ATG5	inhibits	gene	0.60
ALS	inhibits	gene	0.60
AKT	inhibits	gene	0.60
LOX	inhibits	gene	0.60
ACTB	inhibits	gene	0.60
AUTOPHAGY	inhibits	gene	0.60
AMPK	inhibits	gene	0.60
ATP	inhibits	gene	0.60
DNA	inhibits	gene	0.60
CGAS	inhibits	gene	0.60
IRF3	inhibits	gene	0.60
PARP1	inhibits	gene	0.60
AUTOPHAGY	regulates	gene	0.60
NCOA4	regulates	gene	0.60
RNA	regulates	gene	0.60
NEURODEGENERATION	biomarker_for	gene	0.60
NEUROINFLAMMATION	biomarker_for	gene	0.60
NEUROTOXICITY	contributes_to	gene	0.60
TUBULIN	biomarker_for	gene	0.60
INFLAMMATION	biomarker_for	gene	0.60
GFAP	activates	gene	0.60
MTOR	inhibits	gene	0.60
FERROPTOSIS	therapeutic_target	gene	0.60
AADC	regulates	gene	0.60
TRKA	associated_with	gene	0.60
CYP1A2	regulates	gene	0.60
MAO-B	activates	gene	0.60
TAAR1	regulates	gene	0.60
AHR	activates	gene	0.60
GENES	regulates	gene	0.60
CYP1A1	regulates	gene	0.60
ROS	regulates	gene	0.60
ANXIETY	inhibits	gene	0.60
NEUROINFLAMMATION	inhibits	gene	0.60
PARKINSON	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

MAO

Understanding Entity Pages

Wiki Pages (21)

MAO-B Inhibitors for Parkinson's Disease — Investment Landscape Analysis

cbs-psp-daily-action-plan

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

Clinical Management Guide for CBS/PSP

Progressive Supranuclear Palsy (PSP)

Parkinson's Disease

CBS/PSP Supplements Guide

Atypical Parkinsonism

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

PD Combination Therapy Matrix

nhp-validation-animal-model

Therapeutics

Section 162: Advanced Antioxidant and Redox Therapy in CBS/PSP

neuroinflammation

CBS/PSP Treatment Rankings

NRF2 Oxidative Stress Pathway

Alzheimer's Disease

PD Cure Roadmap

rasagiline