TAAR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about TAAR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Trace Amine-Associated Receptor 1 is a GPCR that responds to endogenous trace amines and modulates monoamine neurotransmission, implicated in Parkinson's disease, schizophrenia, and addiction.

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graph TD
    TAAR1["<b>TAAR1</b>"]
    Lymphoma{"Lymphoma"}
    TAAR1 -->|"associated with"| Lymphoma
    Ms{"Ms"}
    TAAR1 -->|"associated with"| Ms
    Inflammation{"Inflammation"}
    TAAR1 -->|"associated with"| Inflammation
    SIGMAR1["SIGMAR1"]
    TAAR1 -->|"associated with"| SIGMAR1
    MYD88["MYD88"]
    TAAR1 -->|"associated with"| MYD88
    PUMA["PUMA"]
    TAAR1 -->|"associated with"| PUMA
    Toll_Like_Receptor(["Toll-Like Receptor"])
    TAAR1 -->|"associated with"| Toll_Like_Receptor
    Oxidative_Stress(["Oxidative Stress"])
    TAAR1 -->|"associated with"| Oxidative_Stress
    Autophagy(["Autophagy"])
    TAAR1 -->|"associated with"| Autophagy
    Pi3K(["Pi3K"])
    TAAR1 -->|"associated with"| Pi3K
    Apoptosis(["Apoptosis"])
    TAAR1 -->|"associated with"| Apoptosis
    Akt(["Akt"])
    TAAR1 -->|"associated with"| Akt
    VEGF["VEGF"]
    VEGF -->|"associated with"| TAAR1
    BAX["BAX"]
    BAX -->|"associated with"| TAAR1
    FIS1["FIS1"]
    FIS1 -->|"associated with"| TAAR1
    TRAF6["TRAF6"]
    TRAF6 -->|"associated with"| TAAR1
    CHOP["CHOP"]
    CHOP -->|"associated with"| TAAR1
    NRF2["NRF2"]
    NRF2 -->|"associated with"| TAAR1
    MTOR["MTOR"]
    MTOR -->|"associated with"| TAAR1
    BECLIN1["BECLIN1"]
    BECLIN1 -->|"associated with"| TAAR1
    BCL2["BCL2"]
    BCL2 -->|"associated with"| TAAR1
    PI3K["PI3K"]
    PI3K -->|"associated with"| TAAR1
    MYD88 -->|"associated with"| TAAR1
    AKT["AKT"]
    AKT -->|"associated with"| TAAR1
    style TAAR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0