concept

PROTO-ONCOGENES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PROTO-ONCOGENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections
0Hypotheses
0Analyses
13Outgoing
7Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NamePROTO-ONCOGENES
Key Genes/ProteinsCYTOKINES, ONCOGENES, AND, APOPTOSIS, CANCER, P53
Related DiseasesTumor, Cancer, ALS
Related PathwaysSignal Transduction, Cell Cycle, Apoptosis

Wiki Pages (20)

Knowledge base pages for this entity

NTF4 Protein

protein · 5111 words

CD2AP Gene — CD2-Associated Protein

gene · 2828 words

MERTK - MER Tyrosine Kinase

gene · 2621 words

SPI1 Gene - PU.1

gene · 2569 words

TYRO3 - TYRO3 Receptor Tyrosine Kinase

gene · 2468 words

Pathway Diagram

graph TD
    PROTO_ONCOGENES["PROTO-ONCOGENES"]
    PROTO_ONCOGENES -->|"involved_in"| Signal_Transduction["Signal Transduction"]
    PROTO_ONCOGENES -->|"inhibits"| Tumor["Tumor"]
    PROTO_ONCOGENES -->|"activates"| Cancer["Cancer"]
    PROTO_ONCOGENES -->|"activates"| ALS["ALS"]
    PROTO_ONCOGENES -->|"activates"| CYTOKINES["CYTOKINES"]
    PROTO_ONCOGENES -->|"inhibits"| ONCOGENES["ONCOGENES"]
    PROTO_ONCOGENES -->|"inhibits"| AND["AND"]
    PROTO_ONCOGENES -->|"activates"| APOPTOSIS["APOPTOSIS"]
    GENES["GENES"] -->|"inhibits"| PROTO_ONCOGENES
    TUMOR_SUPPRESSOR_GENES["TUMOR SUPPRESSOR GENES"] -->|"inhibits"| PROTO_ONCOGENES
    APOPTOSIS -->|"activates"| PROTO_ONCOGENES
    CANCER["CANCER"] -->|"activates"| PROTO_ONCOGENES
    AND -->|"inhibits"| PROTO_ONCOGENES
    P53["P53"] -->|"activates"| PROTO_ONCOGENES
    ONCOGENES -->|"inhibits"| PROTO_ONCOGENES

Outgoing (13)

TargetRelationTypeStr
Signal Transductioninvolved_inpathway0.90
Tumorinhibitsdisease0.65
Canceractivatesdisease0.65
ALSactivatesdisease0.65
CYTOKINESactivatesgene0.60

Incoming (7)

SourceRelationTypeStr
GENESinhibitsgene0.60
TUMOR SUPPRESSOR GENESinhibitsgene0.60
APOPTOSISactivatesgene0.60
CANCERactivatesgene0.60
ANDinhibitsgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found