gene

RAB31

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB31: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

10Connections

0Hypotheses

0Analyses

5Outgoing

5Incoming

Summary

RAB31 is a Rab GTPase involved in trans-Golgi network trafficking and neurodegenerative disease

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🧬 Gene Info

Gene Symbol	RAB31
Full Name	Ras-Related Protein Rab-31
Chromosome	18p11.22
Function	is a member of the Rab GTPase family that plays crucial roles in intracellular membrane trafficking.
Primary Expression	Brain (neurons), TGN, endosomes
Amino Acids	192 aa
UniProt ID	Q9NXA1
NCBI Gene ID	11033
Ensembl ID	ENSG00000170270
OMIM	605628
GeneCards	RAB31
Human Protein Atlas	RAB31
Associated Diseases	Alzheimer's disease, Parkinson's disease
Interactions	RAB7, EGFR, EXOSOMES, ENDOSOMES
KG Connections	10 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RAB31 — AlphaFold Q9NXA1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    RAB31["<b>RAB31</b>"]
    Ms{"Ms"}
    RAB31 -->|"interacts with"| Ms
    neurodegeneration["neurodegeneration"]
    RAB31 -->|"implicated in"| neurodegeneration
    RAB7["RAB7"]
    RAB7 -->|"activates"| RAB31
    EGFR["EGFR"]
    EGFR -->|"interacts with"| RAB31
    EXOSOMES["EXOSOMES"]
    EXOSOMES -->|"activates"| RAB31
    ENDOSOMES["ENDOSOMES"]
    ENDOSOMES -->|"interacts with"| RAB31
    style RAB31 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Ms	interacts_with	disease	0.65
RAB7	activates	gene	0.60
EGFR	interacts_with	gene	0.60
EXOSOMES	activates	gene	0.60
ENDOSOMES	interacts_with	gene	0.60

Incoming (5)

Source	Relation	Type	Str
RAB7	activates	gene	0.60
EGFR	interacts_with	gene	0.60
EXOSOMES	activates	gene	0.60
ENDOSOMES	interacts_with	gene	0.60
AND	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found