gene

SGCE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SGCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections
0Hypotheses
0Analyses
8Outgoing
0Incoming
0Experiments

Summary

Page for SGCE — Sarcoglycan Epsilon

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🧬 Gene Info
Gene SymbolSGCE
Full NameSarcoglycan Epsilon
Chromosome7q21.3
Functionis a gene located on chromosome 7q21.
Primary ExpressionCerebellum, Basal Ganglia, Cerebral Cortex
Exons12
UniProt IDQ9UHI5
NCBI Gene ID9352
Ensembl IDENSG00000127990
OMIM604465
GeneCardsSGCE
Human Protein AtlasSGCE
Associated DiseasesAtherosclerosis
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: SGCE — AlphaFold Q9UHI5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

SGCE — Sarcoglycan Epsilon

gene · 702 words

RAB23 Gene

gene · 1127 words

SLC31A2 — Solute Carrier Family 3 Member 1A2 (SLC31A2)

gene · 691 words

MDS 2026 — Rare Movement Disorders

event · 638 words

Epsilon-Sarcoglycan (SGCE)

protein · 616 words

Proteins

index · 296 words

Pathway Diagram

flowchart TD
    N0["SGCE"]
    N1["Als"]
    N0 -->|"biomarker for"| N1
    N2["Atherosclerosis"]
    N0 -->|"associated with"| N2
    N3["NLRP3"]
    N0 -->|"associated with"| N3
    N4["SLC31A2"]
    N0 -->|"associated with"| N4
    N5["RAB23"]
    N0 -->|"biomarker for"| N5
    N6["CDKN2A"]
    N0 -->|"associated with"| N6
    N7["GLS"]
    N0 -->|"associated with"| N7
    N8["Actin"]
    N0 -->|"associated with"| N8
    N9["neurodegeneration"]
    N0 -->|"implicated in"| N9

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 protein

Outgoing (8)

TargetRelationTypeStr
Alsbiomarker_fordisease0.65
Atherosclerosisassociated_withdisease0.65
NLRP3associated_withgene0.60
SLC31A2associated_withgene0.60
RAB23biomarker_forgene0.60

Incoming (0)

SourceRelationTypeStr
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found