Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SGCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SGCE |
| Full Name | Sarcoglycan Epsilon |
| Chromosome | 7q21.3 |
| Function | is a gene located on chromosome 7q21. |
| Primary Expression | Cerebellum, Basal Ganglia, Cerebral Cortex |
| Exons | 12 |
| UniProt ID | Q9UHI5 |
| NCBI Gene ID | 9352 |
| Ensembl ID | ENSG00000127990 |
| OMIM | 604465 |
| GeneCards | SGCE |
| Human Protein Atlas | SGCE |
| Associated Diseases | Atherosclerosis |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["SGCE"]
N1["Als"]
N0 -->|"biomarker for"| N1
N2["Atherosclerosis"]
N0 -->|"associated with"| N2
N3["NLRP3"]
N0 -->|"associated with"| N3
N4["SLC31A2"]
N0 -->|"associated with"| N4
N5["RAB23"]
N0 -->|"biomarker for"| N5
N6["CDKN2A"]
N0 -->|"associated with"| N6
N7["GLS"]
N0 -->|"associated with"| N7
N8["Actin"]
N0 -->|"associated with"| N8
N9["neurodegeneration"]
N0 -->|"implicated in"| N9
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 disease
class N2 disease
class N3 gene
class N4 gene
class N5 gene
class N6 gene
class N7 gene
class N8 protein| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||