Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC31A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SLC31A2 |
| Full Name | Solute Carrier Family 31 Member 2 (Copper Transporter 2) |
| Chromosome | 9q32 |
| Primary Expression | various tissues and plays complementary roles in copper acquisition, particularly in tissues where CTR1 expression is low or under conditions of high |
| UniProt ID | O15432 |
| NCBI Gene ID | 10552 |
| Ensembl ID | ENSG00000137573 |
| OMIM | 603086 |
| GeneCards | SLC31A2 |
| Human Protein Atlas | SLC31A2 |
| Associated Diseases | Als, Atherosclerosis |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["SLC31A2"]
N1["Als"]
N0 -->|"associated with"| N1
N2["Atherosclerosis"]
N0 -->|"associated with"| N2
N3["RAB23"]
N0 -->|"associated with"| N3
N4["CDKN2A"]
N0 -->|"regulates"| N4
N5["GLS"]
N0 -->|"regulates"| N5
N6["Actin"]
N0 -->|"associated with"| N6
N7["SGCE"]
N7 -->|"associated with"| N0
N8["NLRP3"]
N8 -->|"regulates"| N0
N9["neurodegeneration"]
N0 -->|"implicated in"| N9
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 disease
class N2 disease
class N3 gene
class N4 gene
class N5 gene
class N6 protein
class N7 gene
class N8 geneHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||