protein

SMAD3PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SMAD3PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Incoming

0Experiments

Summary

SMAD Family Member 3 is a SMAD family member. The protein contains the characteristic domain structure including domain descriptions. The molecular weight is approximately 48 kDa, and the protein localizes to Cytoplasm, nucleus.

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🔬 Protein Info

Gene Symbol	SMAD3PROTEIN
Chromosome	15q22
Protein Family	SMAD family (R-SMADs)
Protein Type	Receptor
Function	SMAD Family Member 3 is a SMAD family member. The protein contains the characteristic domain structure including domain descriptions. The molecular weight is approximately 48 kDa, and the protein loca
Subcellular Localization	Cytoplasm, nucleus
Molecular Weight	48 kDa
UniProt ID	P84022
GeneCards	SMAD3PROTEIN
Human Protein Atlas	SMAD3PROTEIN
Protein Name	SMAD Family Member 3
Gene	SMAD3
PDB IDs	1MK2, 1MKS, 1OZ1
Associated Diseases	ALS, Aging, Alzheimer, Crohn'S Disease, Diabetes
Known Drugs/Compounds	lycopene
Interactions	ADAMTS4, AKT, BNIP3L, LC3, TNF, BRD4
KG Connections	374 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SMAD Family Member 3

protein · 595 words

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Pathway Diagram

graph TD
    SMAD3PROTEIN["SMAD3PROTEIN"]
    neurodegeneration["neurodegeneration"]
    SMAD3PROTEIN -->|"implicated_in"| neurodegeneration
    style SMAD3PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found