protein

STAU2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about STAU2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Staufen2 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.

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🔬 Protein Info

Gene Symbol	STAU2PROTEIN
Full Name	Staufen2
Protein Family	Staufen family, RNA-binding proteins
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	~63 kDa (isoform-dependent)
UniProt ID	Q9NUR2
GeneCards	STAU2PROTEIN
Human Protein Atlas	STAU2PROTEIN
N-terminal dsRNA-binding domains (RBDs)	4-5 dsRNA-binding domains that bind to target mRNAs
Staufen domain	C-terminal domain mediating protein-protein interactions
Microtubule-binding region	Maps to N-terminal region for transport
Multiple isoforms	Generated by alternative splicing (STAU2 isoforms 1-5)
Associated Diseases	Als, Amyotrophic Lateral Sclerosis, Ataxia, Dementia, frontotemporal dementia
Known Drugs/Compounds	rapamycin
Interactions	mTOR, MTOR, RNA, STAU1, STAUFEN2
KG Connections	74 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: STAU2PROTEIN — AlphaFold Q9NUR2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Staufen2 Protein

protein · 723 words

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Pathway Diagram

graph TD
    STAU2PROTEIN["STAU2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    STAU2PROTEIN -->|"implicated_in"| neurodegeneration
    style STAU2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning STAU2PROTEIN in their description or question text

No additional research found