Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about STAU2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Staufen2 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
| Gene Symbol | STAU2PROTEIN |
| Full Name | Staufen2 |
| Protein Family | Staufen family, RNA-binding proteins |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Cytoplasm, Dendrites, RNA granules |
| Molecular Weight | ~63 kDa (isoform-dependent) |
| UniProt ID | Q9NUR2 |
| GeneCards | STAU2PROTEIN |
| Human Protein Atlas | STAU2PROTEIN |
| Protein Name | Staufen2 |
| Gene | STAU2 |
| Target | Approach |
| mRNA transport | Transport enhancers |
| Stress granules | Granule modulators |
| STAU2 expression | Gene therapy |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Ataxia, Dementia, Frontotemporal Dementia, Spinocerebellar Ataxia |
| Known Drugs/Compounds | rapamycin |
| Interactions | STAUFEN2, MTOR, mTOR, RNA, STAU1 |
| KG Connections | 77 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
STAU2PROTEIN["STAU2PROTEIN"]
neurodegeneration["neurodegeneration"]
STAU2PROTEIN -->|"implicated_in"| neurodegeneration
style STAU2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||