gene

SUZ12

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SUZ12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections
0Hypotheses
0Analyses
4Outgoing
4Incoming
0Experiments

Summary

Page for SUZ12

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🧬 Gene Info
Gene SymbolSUZ12
Full NameSUZ12 Polycomb Repressive Complex 2 Subunit
AliasesCHET9, JJAZ1
Chromosome17q11.2
Functionencodes an essential zinc finger-containing subunit of Polycomb Repressive Complex 2 (PRC2).
Amino Acids739 aa
Gene TypeProtein-coding
PathwaysMtor
UniProt IDQ15022
Ensembl IDENSG00000178691
OMIM606245
GeneCardsSUZ12
Human Protein AtlasSUZ12
HGNC17101
Entrez Gene23512
Associated Diseasesneurodegeneration
KG Connections8 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING
🔮 Predicted Structure: SUZ12 — AlphaFold Q15022 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (12)

Knowledge base pages for this entity

Canonical Page

SUZ12

gene · 975 words

ASXL1 - Additional Sex Combs Like 1

gene · 2276 words

KDM7A

gene · 1366 words

EZH2 — Enhancer of Zeste Homolog 2

gene · 1311 words

ASXL1 Protein

protein · 1191 words

KDM2B

gene · 1095 words

Pathway Diagram

flowchart TD
    N0["SUZ12"]
    N1["Cancer"]
    N0 -->|"regulates"| N1
    N2["Als"]
    N0 -->|"regulates"| N2
    N3["MTOR"]
    N0 -->|"regulates"| N3
    N4["Mtor"]
    N0 -->|"regulates"| N4
    N5["PI3K"]
    N5 -->|"regulates"| N0
    N6["CANCER"]
    N6 -->|"regulates"| N0
    N7["AKT"]
    N7 -->|"regulates"| N0
    N8["DNA"]
    N8 -->|"regulates"| N0
    N9["neurodegeneration"]
    N0 -->|"implicated in"| N9

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 pathway
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene

Outgoing (4)

TargetRelationTypeStr
Cancerregulatesdisease0.65
Alsregulatesdisease0.65
MTORregulatesgene0.60
Mtorregulatespathway0.60

Incoming (4)

SourceRelationTypeStr
PI3Kregulatesgene0.60
AKTregulatesgene0.60
CANCERregulatesgene0.60
DNAregulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found