Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about abcbl: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ABCB1 |
| Full Name | ATP-Binding Cassette Subfamily B Member 1 (P-glycoprotein) |
| Chromosome | 7q21.12 |
| Protein Type | Transporter |
| Function | of 1,280 amino acids |
| Primary Expression | Brain endothelial cells (blood-brain barrier), Liver, Kidney, Intestine |
| Molecular Weight | 170 kDa |
| Amino Acids | 280 aa |
| Exons | 28 |
| UniProt ID | P08183 |
| NCBI Gene ID | 5243 |
| Ensembl ID | ENSG00000065527 |
| OMIM | 171040 |
| GeneCards | ABCB1 |
| Human Protein Atlas | ABCB1 |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
A["Regulatory elements"] --> B["abcbl gene"]
B --> C["mRNA transcript"]
C --> D["Protein product"]
D --> E["Cellular function"]
E --> F["Disease relevance"]
B --> G["Variant effects"]
G --> F
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
class B gene
class D protein| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ABCBL | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ABCBL | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||