Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about celastrol: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| sorcin | binds_to | protein | 0.95 |
| ROS | promotes | process | 0.95 |
| mitochondrial ROS accumulation | promotes | process | 0.92 |
| ferroptosis | promotes | process | 0.90 |
| Cancer | treats | disease | 0.85 |
| TFEB-mediated tau clearance | causes (enhances TFEB activity to promote selective cleara) | mechanism | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| zwitterionic nanogels | associated_with | compound | 0.92 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 7 hypotheses Top: 0.510
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||