Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CIRCADIAN RHYTHMS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | CIRCADIAN RHYTHMS |
Knowledge base pages for this entity
graph TD
CIRCADIAN_RHYTHMS["CIRCADIAN RHYTHMS"]
CIRCADIAN_RHYTHMS -->|"regulates"| Brain_Lipid_Metabolism["Brain Lipid Metabolism"]
CIRCADIAN_RHYTHMS -->|"contributes to"| Healthy_Brain_Aging["Healthy Brain Aging"]
CLOCK["CLOCK"] -->|"involved_in"| CIRCADIAN_RHYTHMS
BMAL1["BMAL1"] -->|"involved_in"| CIRCADIAN_RHYTHMS
PER["PER"] -->|"involved_in"| CIRCADIAN_RHYTHMS
CRY["CRY"] -->|"involved_in"| CIRCADIAN_RHYTHMS
Glioblastoma["Glioblastoma"] -->|"interacts"| CIRCADIAN_RHYTHMS
time_restricted_eating["time-restricted eating"] -->|"activates"| CIRCADIAN_RHYTHMS| Target | Relation | Type | Str |
|---|---|---|---|
| Brain Lipid Metabolism | regulates | process | 0.95 |
| metabolism | regulates | process | 0.90 |
| Sleep-Wake Cycles | regulates | process | 0.90 |
| Hormone Secretion | regulates | process | 0.90 |
| Healthy Brain Aging | contributes_to | phenotype | 0.80 |
| Neurodegenerative Diseases | associated_with | disease | 0.80 |
| neurodegenerative diseases | implicated_in | disease | 0.80 |
| neurodegeneration | associated_with | disease | 0.70 |
| brain lipid metabolism | influences | process | 0.70 |
| Alzheimer's Disease | associated_with | disease | 0.70 |
| Parkinson's Disease | associated_with | disease | 0.70 |
| neurodegenerative diseases | influences | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CLOCK | involved_in | gene | 0.90 |
| BMAL1 | involved_in | gene | 0.90 |
| MFN2 | regulates | protein | 0.90 |
| Mtnr1B | regulates | protein | 0.90 |
| PER | involved_in | gene | 0.90 |
| CRY | involved_in | gene | 0.90 |
| Glioblastoma | interacts_with | disease | 0.85 |
| CLOCK | regulates | gene | 0.80 |
| Bmal1 | regulates | gene | 0.80 |
| HUNTINGTON | disrupts | disease | 0.80 |
| Clock | regulates | gene | 0.80 |
| Sleep Behavior | associated_with | phenotype | 0.75 |
| BMAL1 | regulates | protein | 0.70 |
| time-restricted eating | activates | process | 0.70 |
| Gut Health | associated_with | phenotype | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||