concept

GLUTAMATERGIC SIGNALING

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLUTAMATERGIC SIGNALING: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections
0Hypotheses
0Analyses
9Outgoing
5Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameGLUTAMATERGIC SIGNALING
Key Genes/ProteinsBDNF
Related DiseasesSTROKE, ALS, ALZHEIMER'S DISEASE

Wiki Pages (20)

Knowledge base pages for this entity

Myoclonus and Cortical Hyperexcitability in Corticobasal Syndrome

mechanism · 6138 words

NPM1 Gene

gene · 5653 words

GRIA3 Gene

gene · 5408 words

CLCN10 — Chloride Voltage-Gated Channel 10

gene · 4939 words

Tau Spreading Mechanism

mechanism · 4818 words

Pathway Diagram

graph TD
    GLUTAMATERGIC_SIGNALING["GLUTAMATERGIC SIGNALING"]
    GLUTAMATERGIC_SIGNALING -->|"contributes to"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    GLUTAMATERGIC_SIGNALING -->|"activates"| cortical_hyperexcitability["cortical hyperexcitability"]
    GLUTAMATERGIC_SIGNALING -->|"activates"| motor_neuron_hyperexcitability["motor neuron hyperexcitability"]
    GLUTAMATERGIC_SIGNALING -->|"regulates"| MOTOR_NEURONS["MOTOR NEURONS"]
    GLUTAMATERGIC_SIGNALING -->|"regulates"| WHITE_MATTER["WHITE MATTER"]
    GLUTAMATERGIC_SIGNALING -->|"regulates"| GRAY_MATTER["GRAY MATTER"]
    GLUTAMATERGIC_SIGNALING -->|"regulates"| NEURON["NEURON"]
    GLUTAMATERGIC_SIGNALING -->|"regulates"| STROKE["STROKE"]
    BIN1["BIN1"] -->|"regulates"| GLUTAMATERGIC_SIGNALING
    EXCITOTOXICITY["EXCITOTOXICITY"] -->|"regulates"| GLUTAMATERGIC_SIGNALING
    CORTEX["CORTEX"] -->|"regulates"| GLUTAMATERGIC_SIGNALING
    ALS["ALS"] -->|"regulates"| GLUTAMATERGIC_SIGNALING
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"regulates"| GLUTAMATERGIC_SIGNALING
    BDNF["BDNF"] -->|"expressed in"| GLUTAMATERGIC_SIGNALING

Outgoing (12)

TargetRelationTypeStr
MOTOR NEURONSregulatescell_type0.35
WHITE MATTERregulatesbrain_region0.35
GRAY MATTERregulatesbrain_region0.35
NEURONregulatescell_type0.35
STROKEregulatesdisease0.35

Incoming (8)

SourceRelationTypeStr
EXCITOTOXICITYregulatesprocess0.35
CORTEXregulatesbrain_region0.35
ALSregulatesdisease0.35
ALZHEIMER'S DISEASEregulatesdisease0.35
BDNFexpressed_ingene0.35

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found