Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEUROVASCULAR UNIT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEUROVASCULAR UNIT |
| Related Diseases | BRAIN DISORDERS |
Knowledge base pages for this entity
graph TD
NEUROVASCULAR_UNIT["NEUROVASCULAR UNIT"]
NEUROVASCULAR_UNIT -->|"component_of"| Blood_Brain_Barrier["Blood-Brain Barrier"]
NEUROVASCULAR_UNIT -->|"contributes to"| Neuroinflammation["Neuroinflammation"]
Neurons["Neurons"] -->|"component_of"| NEUROVASCULAR_UNIT
Endothelial_Cells["Endothelial Cells"] -->|"component_of"| NEUROVASCULAR_UNIT
Pericytes["Pericytes"] -->|"component_of"| NEUROVASCULAR_UNIT
Vascular_Smooth_Muscle_Cells["Vascular Smooth Muscle Cells"] -->|"component_of"| NEUROVASCULAR_UNIT
Glial_Cells["Glial Cells"] -->|"component_of"| NEUROVASCULAR_UNIT
Extracellular_Matrix["Extracellular Matrix"] -->|"component_of"| NEUROVASCULAR_UNIT
AMPK["AMPK"] -->|"regulates"| NEUROVASCULAR_UNIT| Target | Relation | Type | Str |
|---|---|---|---|
| BRAIN DISORDERS | implicated_in | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Neurons | component_of | cell_type | 0.95 |
| Endothelial Cells | component_of | cell_type | 0.95 |
| Pericytes | component_of | cell_type | 0.95 |
| Vascular Smooth Muscle Cells | component_of | cell_type | 0.95 |
| Glial Cells | component_of | cell_type | 0.95 |
| specialized microvascular endothelial cells | associated_with | cell_type | 0.95 |
| Astrocytes | involved_in | cell_type | 0.95 |
| Extracellular Matrix | component_of | process | 0.90 |
| glial cell activation | modulates | process | 0.90 |
| KCNK2 | involved_in | gene | 0.85 |
| Pericytes | involved_in | cell_type | 0.82 |
| PDGFB | modulates | gene | 0.80 |
| PDGFRB | modulates | gene | 0.80 |
| LRP-1 | expressed_in | gene | 0.80 |
| AMPK | regulates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||