PDGFB

Understanding Entity Pages

This page aggregates everything SciDEX knows about PDGFB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PDGFB is a gene implicated in neurodegeneration research. Key relationships include: associated with, regulates, expressed in. Associated with ALS, Aging, Als. Connected to 46 entities in the SciDEX knowledge graph.

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graph TD
    PDGFB["<b>PDGFB</b>"]
    Aging{"Aging"}
    PDGFB -->|"associated with"| Aging
    Ms{"Ms"}
    PDGFB -->|"associated with"| Ms
    Parkinson{"Parkinson"}
    PDGFB -->|"associated with"| Parkinson
    Als{"Als"}
    PDGFB -->|"associated with"| Als
    PDGFB -->|"regulates"| Ms
    PDGFB -->|"inhibits"| Ms
    Fibrosis{"Fibrosis"}
    PDGFB -->|"expressed in"| Fibrosis
    PDGFB -->|"expressed in"| Als
    ALS{"ALS"}
    PDGFB -->|"associated with"| ALS
    Fahr_disease{"Fahr_disease"}
    PDGFB -->|"causes"| Fahr_disease
    Blood_Brain_Barrier(["Blood-Brain Barrier"])
    PDGFB -->|"associated with"| Blood_Brain_Barrier
    PDGFRB["PDGFRB"]
    PDGFB -->|"associated with"| PDGFRB
    JUN["JUN"]
    JUN -->|"associated with"| PDGFB
    JAM2["JAM2"]
    JAM2 -->|"associated with"| PDGFB
    PDGFRB -->|"associated with"| PDGFB
    PDGFRB -->|"regulates"| PDGFB
    GENES["GENES"]
    GENES -->|"regulates"| PDGFB
    GENES -->|"inhibits"| PDGFB
    PDGFRB -->|"expressed in"| PDGFB
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MITOCHONDRIAL_DYSFUNCTION -->|"associated with"| PDGFB
    GENES -->|"associated with"| PDGFB
    XPR1["XPR1"]
    XPR1 -->|"associated with"| PDGFB
    SLC20A2["SLC20A2"]
    SLC20A2 -->|"associated with"| PDGFB
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"associated with"| PDGFB
    style PDGFB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0