Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RADIORESISTANCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | RADIORESISTANCE |
Knowledge base pages for this entity
graph TD
RADIORESISTANCE["RADIORESISTANCE"]
HSPG2["HSPG2"] -->|"regulates"| RADIORESISTANCE
Perlecan["Perlecan"] -->|"regulates"| RADIORESISTANCE
CDK2_TRIM32_STAT3["CDK2/TRIM32/STAT3"] -->|"regulates"| RADIORESISTANCE
SDC1["SDC1"] -->|"contributes to"| RADIORESISTANCE
TGM2["TGM2"] -->|"contributes to"| RADIORESISTANCE
STAT3["STAT3"] -->|"promotes"| RADIORESISTANCE
Cell_Adhesion_Mediated_Signali["Cell Adhesion-Mediated Signaling"] -->|"mediates"| RADIORESISTANCE
Radiotherapy["Radiotherapy"] -->|"causes"| RADIORESISTANCE| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| HSPG2 | regulates | gene | 0.95 |
| Perlecan | regulates | protein | 0.95 |
| CDK2/TRIM32/STAT3 | regulates | pathway | 0.93 |
| SDC1 | contributes_to | protein | 0.92 |
| TGM2 | contributes_to | protein | 0.92 |
| STAT3 | promotes | protein | 0.92 |
| Cell Adhesion-Mediated Signaling | mediates | pathway | 0.90 |
| Radiotherapy | causes | process | 0.90 |
| PERLECAN | modulates | protein | 0.90 |
| Cell Adhesion-Mediated Signaling | involved_in | pathway | 0.90 |
| CDK2 | promotes | gene | 0.88 |
| Extracellular Matrix | involved_in | process | 0.85 |
| Extracellular Matrix | contributes_to | structure | 0.85 |
| Matrix Remodeling | associated_with | process | 0.85 |
| Matrix Remodeling | contributes_to | process | 0.85 |
| cell adhesion-mediated signaling | contributes_to | pathway | 0.85 |
| SDC1 | promotes | gene | 0.85 |
| TGM2 | promotes | gene | 0.85 |
| autophagy | promotes | process | 0.85 |
| Matrisome Components | associated_with | compound | 0.82 |
| SNORA28 | causes | gene | 0.80 |
| Adhesion Signaling Complexes | contributes_to | mechanism | 0.80 |
| matrisome | drives | pathway | 0.80 |
| adhesome | modulates | pathway | 0.75 |
| SDC1 | associated_with | protein | 0.70 |
| TGM2 | associated_with | protein | 0.70 |
| SDC1 | activates | protein | 0.70 |
| TGM2 | activates | protein | 0.70 |
| Integrin Expression | associated_with | process | 0.70 |
| TGM2 | biomarker_for | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||