🧫

iPSC-NPC effects on astrocytes in vitro ICH model

active
experiment Created: 2026-04-10T23:10:15 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-545ecac0-8b8e-4dc1-b999-1
🧫 Experiment Protocol Cell Biologyproposed
Related Entities
AMPK, mTOR, GFAP, SQSTM1, LC3
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T23:10:15.519965'}
p_valueNone
protocolco-culture of iPSC-NPCs with astrocytes, protein and mRNA expression analysis, immunofluorescence, mTOR inhibitor treatment
effect_sizeNone
sample_sizeNone
source_pmid41921697
extracted_at2026-04-10T16:10:15.375660
_schema_version1
experiment_typecell_biology
success_criteriainhibited AMPK phosphorylation, promoted mTOR activation, reduced autophagy markers
expected_outcomesiPSC-NPCs would protect astrocytes and modulate autophagy pathways
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
742
Outgoing
53
0 supporting 0 contradicting 0 neutral
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