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MAP1LC3A Gene

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-lc3
Related Entities
LC3
Metadata
sluggenes-lc3
entity_typegene
kg_node_idLC3
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (226)
mentions🧪SASP-Mediated Complement Cascade Amplification90%
related🧪SASP-Mediated Complement Cascade Amplification90%
mentions🧫CLOCK/BMAL1 regulation of ICC autophagy in GERD model70%
mentions🧫iPSC-NPC effects on astrocytes in vitro ICH model70%
mentions🧫iPSC-NPC transplantation in ICH animal model70%
mentions🧫s:** - Dose-response studies showing therapeutic window with70%
mentions🧫P2RY12 regulation of autophagy in VSMCs70%
mentions🧫Autophagy Enhancement Drug Screening for Neurodegeneration70%
mentions🧫Selective Vulnerability of Dopaminergic Neurons — Mechanism 70%
mentions🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%
mentions🧫Exercise-BDNF-Mitophagy Biomarker Study in PD70%
mentions🧫Macroautophagy Dysfunction in PD - Experiment Design70%
mentions🧫Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel70%
mentions🧫Sirtuin Dysfunction Validation in Parkinson's Disease70%
mentions🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an70%
related🧫Proposed experiment from debate on Synaptic pruning by micro70%
related🧫Proposed experiment from debate on Senolytics targeting p16/70%
related🧫Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?70%
related🧫Experiment: Autoimmune Hypothesis Testing in AD70%
related🧫Mixed Pathology Effects on Parkinson's Disease Progress70%
related🧫Normal Aging to Alzheimer's Disease Transition Trigger 70%
related🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des70%
related🧫Proposed experiment from debate on Synaptic pruning by micro70%
related🧫Proposed experiment from debate on Senolytics targeting p16/70%
related🧫Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?70%
related🧫Experiment: Autoimmune Hypothesis Testing in AD70%
related🧫Mixed Pathology Effects on Parkinson's Disease Progress70%
related🧫Normal Aging to Alzheimer's Disease Transition Trigger 70%
related🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des70%
related🧫Macroautophagy Dysfunction in PD - Experiment Design70%
related🧫CLOCK/BMAL1 regulation of ICC autophagy in GERD model63%
related🧫iPSC-NPC effects on astrocytes in vitro ICH model63%
related🧫iPSC-NPC transplantation in ICH animal model63%
related🧫s:** - Dose-response studies showing therapeutic window with63%
related🧫P2RY12 regulation of autophagy in VSMCs63%
related🧫Autophagy Enhancement Drug Screening for Neurodegeneration63%
related🧫Selective Vulnerability of Dopaminergic Neurons — Mechanism 63%
related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De63%
related🧫Exercise-BDNF-Mitophagy Biomarker Study in PD63%
related🧫Macroautophagy Dysfunction in PD - Experiment Design63%
related🧫Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel63%
related🧫Sirtuin Dysfunction Validation in Parkinson's Disease63%
related🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an63%
see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%
see_also📖ACTB Gene60%
see_also📖ap2a160%
see_also📖AP2M1 Gene60%
see_also📖ARAF Gene60%
see_also📖CDK12 — Cyclin-Dependent Kinase 1260%
see_also📖DIABLO60%
see_also📖ECSIT — Evolutionarily Conserved Signaling Intermediate in T60%
see_also📖ELMO1 - Engulfment and Cell Motility 160%
see_also📖MAP3K7 Gene60%
see_also📖MELK Gene60%
see_also📖nfatc260%
see_also📖NSF Gene60%
see_also📖SFN Gene60%
see_also📖SMAD2 Gene60%
see_also📖TPX260%
see_also📖TRIM25 Gene (Tripartite Motif Containing 25)60%
see_also📖WIPI3 Gene60%
see_also📖WIPI4 Gene60%
see_also📖ACLY Inhibition Rescues Alpha-Synuclein Autophagy60%
see_also📖iPSC-Derived Dopaminergic Neurons60%
see_also📖A-Raf Protein60%
see_also📖ATG16L2 Gene60%
see_also📖atp6v0d160%
see_also📖CDKN1B — Cyclin-Dependent Kinase Inhibitor 1B60%
see_also📖L1CAM (L1 Cell Adhesion Molecule)60%
see_also📖PDPK1 Gene60%
see_also📖pnpla660%
see_also📖RAB2A Gene60%
see_also📖tufm60%
see_also📖p62/SQSTM1 (Sequestosome-1)60%
see_also📖trim260%
see_also📖GDAP1 — Ganglioside-Induced Differentiation-Associated Prote60%
see_also📖Sulforaphane and Nrf2 Activation for Neuroprotection60%
see_also📖Hippocampus60%
see_also📖ATG17 Gene60%
see_also📖MAP1LC3B2 Gene60%
see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%
see_also📖Dementia Australia60%
see_also📖atg10160%
see_also📖EEF2K — Eukaryotic Elongation Factor 2 Kinase60%
see_also📖FKBP1A60%
see_also📖SRSF160%
see_also📖TRAF360%
see_also📖VPS16 Gene60%
see_also📖VPS33A Gene60%
see_also📖VPS16 Protein60%
see_also📖ABCD3 Gene60%
see_also📖ABCG1 Gene60%
see_also📖BMPR1A — Bone Morphogenetic Protein Receptor Type 1A60%
see_also📖MAP1B Gene60%
see_also📖retreg360%
see_also📖WDFY3 Gene60%
see_also📖WIPI1 Gene60%
see_also📖MAP1B Protein60%
see_also📖Efferocytosis in Neurodegeneration60%
see_also📖CSNK2B Gene60%
see_also📖MARK2 Gene60%
see_also📖NLR Family Member X160%
see_also📖pex1460%
see_also📖PLK2 Gene60%
see_also📖PRKCQ60%
see_also📖TIGAR - TP53-Induced Glycolysis and Apoptosis Regulator60%
see_also📖TOMM40 Gene60%
see_also📖UBB — Ubiquitin B60%
see_also📖Acupuncture Therapy for Parkinson's Disease60%
see_also📖Acupuncture Therapy for Neurodegeneration60%
see_also📖Acupuncture Therapy for Parkinson's Disease60%
see_also📖Acupuncture and TCM for Atypical Parkinsonism60%
see_also📖NRF2 Activator Therapy60%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th55%
mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
mentions🔬What are the mechanisms underlying senolytic therapy for age50%
mentions🔬What are the mechanisms underlying sleep disruption as cause50%
mentions🔬Investigate prion-like spreading of tau pathology through co50%
mentions🧫Autophagy Enhancement Drug Screening for Neurodegeneration50%
mentions🧫Macroautophagy Dysfunction in PD - Experiment Design50%
mentions🧫Mutant Huntingtin (mHTT) Clearance Mechanisms — Therapeutic 50%
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%
mentions🧪Circadian-Synchronized Proteostasis Enhancement50%
mentions🧪VCP-Mediated Autophagy Enhancement50%
mentions🧪PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor50%
mentions🧪APOE-Dependent Autophagy Restoration50%
mentions🧪Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption50%
mentions🧪Transcriptional Autophagy-Lysosome Coupling50%
mentions🧪Lysosomal Enzyme Trafficking Correction50%
mentions🧪Circadian Clock-Autophagy Synchronization50%
mentions🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
mentions🧪Circadian Rhythm Entrainment of Reactive Astrocytes50%
mentions🧪Optogenetic Microglial Deactivation via Engineered Inhibitor50%
mentions🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri50%
mentions🧪DNMT1-Targeting Antisense Oligonucleotide Reset50%
mentions🧪FOXO3-Longevity Pathway Epigenetic Reprogramming50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪Phase-Separated Organelle Targeting50%
mentions🧪RNA Granule Nucleation Site Modulation50%
mentions🧪Selective HDAC3 Inhibition with Cognitive Enhancement50%
mentions🧪HDAC3-Selective Inhibition for Clock Reset50%
mentions🧪Mitochondrial Transfer Pathway Enhancement50%
mentions🧪Partial Neuronal Reprogramming via Modified Yamanaka Cocktai50%
mentions🧪Microglial Purinergic Reprogramming50%
mentions🧪Purinergic P2Y12 Inverse Agonist Therapy50%
mentions🧪Extracellular Matrix Stiffness Modulation50%
mentions🧪Metabolic Circuit Breaker via Lipid Droplet Modulation50%
mentions🧪Perforant Path Presynaptic Terminal Protection Strategy50%
mentions🧪Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat50%
mentions🧪R-Loop Resolution Enhancement Therapy50%
mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%
mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%
mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy50%
mentions🧪Cryptic Exon Silencing Restoration50%
mentions🧪Glycine-Rich Domain Competitive Inhibition50%
mentions🧪Cross-Seeding Prevention Strategy50%
mentions🧪TFAM overexpression creates mitochondrial donor-recipient gr50%
mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering50%
mentions🧪Low Complexity Domain Cross-Linking Inhibition50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Quantum Coherence Disruption in Cellular Communication50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying sleep disruption as cause50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying rna binding protein dysre50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
related🔬Epigenetic reprogramming in aging neurons50%
related🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc50%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Mitochondrial-Lysosomal Contact Site Engineering40%
related🧪HSP90-Tau Disaggregation Complex Enhancement40%
related🧪VCP-Mediated Autophagy Enhancement40%
related🧪Senescent Cell Mitochondrial DNA Release40%
related🧪SASP-Mediated Cholinergic Synapse Disruption40%
related🧪Noradrenergic-Tau Propagation Blockade40%
related🧪Adenosine-Astrocyte Metabolic Reset40%
related🧪LRP1-Dependent Tau Uptake Disruption40%
related🧪Extracellular Vesicle Biogenesis Modulation40%
related🧪SASP-Mediated Complement Cascade Amplification40%
related🧪Autophagosome Maturation Checkpoint Control40%
related🧪Hypocretin-Neurogenesis Coupling Therapy40%
related🧪Synaptic Vesicle Tau Capture Inhibition40%
related🧪Senescence-Induced Lipid Peroxidation Spreading40%
related🧪SASP-Driven Aquaporin-4 Dysregulation40%
related🧪Orexin-Microglia Modulation Therapy40%
related🧪Lysosomal Membrane Repair Enhancement40%
related🧪Sleep Spindle-Synaptic Plasticity Enhancement40%
related🧪Lysosomal Calcium Channel Modulation Therapy40%
related🧪Transcriptional Autophagy-Lysosome Coupling40%
related🧪TREM2-mediated microglial tau clearance enhancement40%
related🧪Lysosomal Positioning Dynamics Modulation40%
related🧪Lysosomal Enzyme Trafficking Correction40%
related🧪Circadian Clock-Autophagy Synchronization40%
related🧪Senescence-Associated Myelin Lipid Remodeling40%
related🧪Senescence-Activated NAD+ Depletion Rescue40%
related🧪Circadian Glymphatic Rescue Therapy (Melatonin-focused)40%
related🧪Trans-Synaptic Adhesion Molecule Modulation40%
related🧪CYP46A1 Overexpression Gene Therapy40%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%
related🔬What are the mechanisms underlying senolytic therapy for age40%
related🔬Senolytics targeting p16/p21+ senescent astrocytes and micro40%
related🔬Investigate prion-like spreading of tau pathology through co40%
related🔬Tau propagation mechanisms and therapeutic interception poin40%
related🔬What are the mechanisms underlying sleep disruption as cause40%
related🔬Sleep disruption as cause and consequence of neurodegenerati40%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa40%
related🔬Multiple NDDs converge on autophagy-lysosome dysfunction. Ar40%
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