gene 797 words KG: APLP2 2026-03-27
kind:genesection:genestopic:alzheimerstopic:down-syndromestate:published
Contents

APLP2 Gene

🧬 Gene Info
Gene SymbolAPLP2
Full NameAmyloid Beta Precursor-Like Protein 2
AliasesAmyloid Precursor-Like Protein 2
Chromosome15q24.2
Functionencodes a protein of approximately 763 amino acids.
Primary Expressionneurons, astrocytes, oligodendrocytes, and microglia, with regional distribution in cerebral cortex, hippocampus, cerebellum, thalamus, and hypothalam
Molecular Weight87 kDa
Amino Acids763 aa
UniProt ID[Q06481](https://www.uniprot.org/uniprot/Q06481)
Ensembl IDENSG00000145087
GeneCardsAPLP2
Human Protein AtlasAPLP2
Associated DiseasesAls
InteractionsAKT, ADAM10, APP, ALZHEIMER'S DISEASE, APOPTOSIS, APLP1
KG Connections39 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

APLP2 protects_against APLP1
APLP2 activates AKT
APLP2 protects_against APP
APLP2 activates ADAM10
APLP2 regulates APLP1
APLP2 regulates NPAS4
APLP2 regulates APP
APLP2 associated_with APP
APLP2 associated_with APLP1
APLP2 targets APP