| Gene Symbol | APOA1 |
| Full Name | Apolipoprotein A1 |
| Chromosome | Chr11q23.3 |
| Function | The APOA1 gene encodes Apolipoprotein A1, the primary protein component of high-density lipoprotein (HDL) particles. |
| Subcellular Localization | </strong></td><td>Secreted, plasma HDL</td></tr> |
| UniProt ID | P02647 |
| NCBI Gene ID | 335 |
| Ensembl ID | ENSG00000118137 |
| OMIM | 107680 |
| GeneCards | APOA1 |
| Human Protein Atlas | APOA1 |
| Amphipathic helices | 10-11 tandem amphipathic helices |
| LCAT activation site | N-terminal region |
| Phospholipid binding | C-terminal domain |
| HDL binding | Multiple regions contribute |
| Associated Diseases | AD, Als, Alzheimer, AMI, ARM |
| Interactions | 4E-BP1, ABCA1, abca2, ABCA2, ABCG1, ACTB |
| KG Connections | 291 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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