cell 664 words KG: CA1
Contents

Hippocampal CA1 Pyramidal Neurons

🧫 Cell Type Info
Cell TypeCA1
Also Known AsCA-I, Carbonate dehydratase I
Key PathwayspH regulation, CO2 transport
Associated DiseasesMetabolic acidosis
Related GenesAMYLOID, APP, GABRA1, HDAC3
Linked Hypotheses232 hypotheses

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Related Hypotheses (22)

Hippocampal CA3-CA1 synaptic rescue via DHHC2-mediated PSD95
Score: 0.89
Gamma entrainment repairs cross-regional phase-amplitude cou
Score: 0.83
miR-33 Antisense Oligonucleotide Hyper-Lipidation Strategy
Score: 0.82
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Closed-loop transcranial focused ultrasound targeting CA1 PV
Score: 0.80
HDL/apoE Particle Remodeling as a Therapeutic Switch for CAA
Score: 0.77
Selective LXRβ agonists restore ABCA1/ABCG1 expression and A
Score: 0.76
APOE4 astrocytes exhibit impaired cholesterol efflux via ABC
Score: 0.76
Closed-loop focused ultrasound targeting CA1 PV interneurons
Score: 0.75
H3: APOE4 Impairs Cholesterol Trafficking, Triggering Astroc
Score: 0.72
APOE4-Specific Microglial Metabolic Rescue
Score: 0.71
Membrane Cholesterol Gradient Modulators
Score: 0.71
APOE4 hypolipidation and ABCA1 mistrafficking impair cholest
Score: 0.69
TREM2-dependent microglial lipid handling in Alzheimer's dis
Score: 0.65
BDNF-mediated hippocampal synaptic rescue as a modifier of C
Score: 0.60
Low-Intensity tFUS Modulation of EC-DG/EC-CA1 Perforant Path
Score: 0.54
SREBP-2 Direct Inhibition Hyper-Lipidation Strategy
Score: 0.49
SREBF2 Direct Activator Hyper-Lipidation Strategy
Score: 0.38
ABCA1 Upregulation via LXRβ Agonism to Enhance Cholesterol E
Score: 0.38
miR-33 Antisense-Enhanced APOE4 Lipidation as Senolytic Timi
Score: 0.38
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Knowledge Graph (12 edges)

HDAC3 associated_with CA1
ketamine activates CA1
CA1 co_discussed CORTEX
CA1 co_discussed CX3CR1
CA1 co_discussed STRIATUM
ACHE protects_against CA1
CA1 protects_against GFAP
CA1 protects_against NEURON
CA1 protects_against NEURONS
CA1 protects_against PYRAMIDAL

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