gene 939 words KG: CLEC7A
Contents

CLEC7A Gene

🧬 Gene Info
Gene SymbolCLEC7A
Protein TypeReceptor
FunctionCLEC7A encodes a type II transmembrane protein with an extracellular C-type lectin domain and an intracellular immunoreceptor tyrosine-based activation motif (ITAM)-like hemITAM.
PathwaysAmyloid, unfolded protein response, lipid metabolism
Ensembl IDENSG00000172243
GeneCardsCLEC7A
Human Protein AtlasCLEC7A
NFATgene transcription for immune activation
CARD9/BCL10/MALT1inflammasome-independent cytokine production
Associated Diseasesischemic stroke, Parkinson's disease
InteractionsAKT3, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APOE, AXL
KG Connections53 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CLEC7A regulates Gal3
CLEC7A regulates TREM2
CLEC7A activates Syk
CLEC7A regulates NOX2
CLEC7A associated_with ischemic stroke
APOE activates CLEC7A
CLEC7A activates TREM2
AXL activates CLEC7A
CD9 activates CLEC7A
CLEC7A activates CTSB

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.