| Gene Symbol | NOX2 |
| Function | Direct microbial killing: Superoxide and derivatives |
| Primary Expression | hippocampus |
| Molecular Weight | 65 kDa |
| Amino Acids | 570 aa |
| Exons | 23 |
| Pathways | Oxidative Stress, oxidative stress response, Endocytosis, Immune Response, Mtor |
| GeneCards | NOX2 |
| Human Protein Atlas | NOX2 |
| Interactor | Relationship |
| p22phox | Membrane subunit |
| p47phox | Cytosolic organizer |
| p67phox | Cytosolic activator |
| Rac | Small GTPase |
| [Nrf2](/proteins/nrf2) | Antioxidant response |
| Associated Diseases | Alzheimer, Parkinson, Traumatic Brain Injury |
| Known Drugs/Compounds | levodopa |
| Interactions | AKT, GFAP, SRC, TLR4, TNF, EXOSOMES |
| KG Connections | 182 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |