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Cognition Therapeutics

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Related Hypotheses (122)

Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61
LRP1-Dependent Tau Uptake Disruption
Score: 0.60
Glycosaminoglycan Template Disruption Approach
Score: 0.60
Netrin-1 Gradient Restoration
Score: 0.59
VCP-Mediated Autophagy Enhancement
Score: 0.59
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
Lysosomal Membrane Repair Enhancement
Score: 0.54
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Cryptic Exon Silencing Restoration
Score: 0.53
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.51
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
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Related Analyses (28)

Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (7)

prefrontal-cortex
brain_region · KG edge: regulates
TFEB (Redirect)
redirect · KG edge: promotes
AQP4 (Aquaporin-4 Gene)
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: activates
COMT Gene
gene · KG edge: regulates

Knowledge Graph (8 edges)

LCPUFA Supplementation protects_against Cognition
BDNF associated_with Cognition
Urolithin A associated_with Cognition
TET2 modulates Cognition
Dentate Gyrus involved_in Cognition
Caffeine for Cognition in AD (NCT04570085) references BACE1
BEACoN Study - Biomarker Exploration in Aging, Cognition and Neurodegeneration references APOE
Caffeine modulates Cognition

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