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disease 767 words KG: ent-dise-789b2442
Contents

Investment Landscape: Alzheimer's Disease

Disease Info
PHASE1480
PHASE1, PHASE2113
PHASE2636
PHASE2, PHASE368
PHASE3321
PHASE4168
NA2082
Not Applicable970
RECRUITING741
ACTIVE_NOT_RECRUITING200
NOT_YET_RECRUITING267
COMPLETED2529
DatabasesOMIMOrphanetClinicalTrialsPubMed

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🌐 Cross-references

OMIMMeSHWikipedia

Related Hypotheses (28)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.95ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.89Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75APOE Isoform Expression Across Glial Subtypes
Score: 0.74SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli
Score: 0.67TREM2-mediated microglial tau clearance enhancement
Score: 0.62LRP1-Dependent Tau Uptake Disruption
Score: 0.60VCP-Mediated Autophagy Enhancement
Score: 0.59Extracellular Vesicle Biogenesis Modulation
Score: 0.58Synaptic Vesicle Tau Capture Inhibition
Score: 0.58HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54Purinergic Signaling Polarization Control
Score: 0.71Mechanosensitive Ion Channel Reprogramming
Score: 0.70
pg 1/2Next →

Related Analyses (21)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedGene expression changes in aging mouse brain predicting neur
neurodegeneration · completed

Related Experiments (30)

Down Syndrome Alzheimer's Disease: Mechanisms and Therapeuti
clinical · proposed · Score: 0.40ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40Plasma ATN biomarkers across AD continuum in Chilean cohort
clinical · proposed · Score: 0.95GWAS of plasma GFAP in East Asian cohort
exploratory · proposed · Score: 0.95

See Also (15)

GFAP in Alzheimer's Disease
biomarker · Pages share 18 hypothesesOlfactory Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypothesesAlzheimer's Disease Biomarkers
biomarker · Pages share 18 hypothesesASL Perfusion Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypothesesNPTX1 and NPTXR CSF Markers Predict Alzheimer's Disease
biomarker · Pages share 21 hypotheses

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