gene 2,004 words KG: FEN1
Contents

FEN1 — Flap Endonuclease 1

🧬 Gene Info
Gene SymbolFEN1
Full NameFlap Endonuclease 1
Chromosome19q13.3
FunctionFEN1 recognizes specific DNA structures through its DNA binding domain and coordinates cleavage at the flap-base junction 200345-8/fulltext).
Primary ExpressionHippocampus, Cerebral cortex, Cerebellum, Substantia nigra
Molecular Weight43 kDa
UniProt IDP39748
NCBI Gene ID2237
Ensembl IDENSG00000163945
OMIM600406
GeneCardsFEN1
Human Protein AtlasFEN1
InteractionsAKT, App, CANCER, DNA, NEURODEGENERATIVE DISEASES, NEURODEGENERATIVE DISORDERS
KG Connections45 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

XPG inhibits FEN1
SETX activates FEN1
TDP1 inhibits FEN1
PNKP activates FEN1
FEN1 inhibits XPF
FEN1 activates XRCC1
XPF inhibits FEN1
FEN1 activates SETX
FEN1 activates PNKP
FEN1 inhibits TDP1

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