| Gene Symbol | FIG4 |
| Full Name | FIG4 Phosphatase Homolog |
| Protein Type | Phosphatase |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Amino Acids | 559 aa |
| Pathways | PI3K |
| Ensembl ID | ENSG00000112367 |
| GeneCards | FIG4 |
| Human Protein Atlas | FIG4 |
| VAC14 | scaffolds the PI(3,5)P2 synthesis complex with FIG4 and PIKFYVE |
| PIKFYVE | phosphorylates PI3P to generate PI(3,5)P2 |
| FYCO1 | interacts with PI3P for autophagosome-lysosome fusion |
| VPS34/PIK3C3 | class III PI3K that produces PI3P |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Dementia, frontotemporal dementia, Ftd |
| Interactions | C9ORF72, C9ORF72 REPEAT EXPANSION |
| KG Connections | 131 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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