gene 1,712 words KG: GDI2
Contents

GDI2 Gene

🧬 Gene Info
Gene SymbolGDI2
Full NameGDP Dissociation Inhibitor 2
Chromosome10p15.3
Functionis a critical regulatory protein that controls the cycling of RAB GTPases between their active GTP-bound and inactive GDP-bound states[@pfeffer1996].
Primary ExpressionUbiquitous, high in brain
Subcellular LocalizationCytosol and associated with various membrane compartments
Molecular Weight51 kDa
Amino Acids467 aa
Exons13
UniProt ID[P50395](https://www.uniprot.org/uniprot/P50395)
Ensembl IDENSG00000123136
OMIM602134
GeneCardsGDI2
Human Protein AtlasGDI2
Molecular weight~53 kDa
Associated DiseasesAls, Alzheimer
Known Drugs/Compoundsaducanumab
InteractionsCAPZB, CD81, NDUFA4, NDUFS7, PLCB1, Proteins
KG Connections35 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CD81 regulates GDI2
GDI2 regulates MAG
GDI2 regulates HK1
GDI2 regulates PLCB1
GDI2 regulates NDUFS7
GDI2 regulates CAPZB
GDI2 regulates NDUFA4
HK1 regulates GDI2
CAPZB regulates GDI2
GDI2 regulates CD81

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