| Gene Symbol | BMPR2 |
| Full Name | Bone Morphogenetic Protein Receptor Type 2 |
| Chromosome | 2q33.1 |
| Protein Type | Serine/Threonine Kinase |
| Function | encodes a constitutively active type II serine/threonine kinase receptor that plays critical roles in Bone Morphogenetic Protein (BMP) signaling pathways [@uzdens2018]. |
| Primary Expression | astrocytes and regulates their function [@wang2019]: |
| Amino Acids | 1038 aa |
| Pathways | MAPK pathway, MAPK signaling, PI3K |
| UniProt ID | [Q13873](https://www.uniprot.org/uniprot/Q13873) |
| Ensembl ID | ENSG00000153208 |
| OMIM | 600799 |
| GeneCards | BMPR2 |
| Human Protein Atlas | BMPR2 |
| Extracellular domain | Ligand-binding region with cysteine-rich domain |
| Transmembrane domain | Single-pass helix anchoring the receptor |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | BMPR1A, BMPR1B |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |