gene 2,283 words KG: CLN1 2026-03-27
kind:genesection:genesstate:publishedtopic:alzheimers
Contents

CLN1 (PPT1) — Palmitoyl-Protein Thioesterase 1

🧬 Gene Info
Gene SymbolCLN1
Full NamePalmitoyl-Protein Thioesterase 1
Chromosome1p34.2
Protein TypeEnzyme
Functionencodes a protein of 306 amino acids with a molecular weight of approximately 34 kDa.
Primary Expressionneurons and regulates synaptic vesicle proteins[@lin2021]: - Synaptic vesicle cycling: Removes palmitoyl groups from vesicle proteins - Neurotra
Molecular Weight34 kDa
Amino Acids306 aa
Exons9
UniProt IDO00624
NCBI Gene ID1204
Ensembl IDENSG00000132128
OMIM256000
GeneCardsCLN1
Human Protein AtlasCLN1
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsIGF1, PI3K
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph