gene 786 words KG: COX15
Contents

COX15 — Cytochrome C Oxidase Assembly Factor 15

🧬 Gene Info
Gene SymbolCOX15
Full NameCytochrome C Oxidase Assembly Factor 15
Chromosome10q24.2
FunctionCOX15 plays a crucial role in the final steps of heme A synthesis
Primary Expressionall tissues with high energy demands: - Heart and skeletal muscle (highest expression) - Brain (neurons and glia) - Liver and kid
Molecular Weight42 kDa
UniProt ID[Q7B433](https://www.uniprot.org/uniprot/Q7B433)
Ensembl IDENSG00000074981
OMIM603646
GeneCardsCOX15
Human Protein AtlasCOX15
Associated Diseasesneurodegeneration
InteractionsATP, COX4I1, COX7A1, COX8A, NDUFA12, NDUFA5
KG Connections21 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71

Related Analyses (2)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (9)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
PEX3 Gene - Peroxisome Biogenesis Factor 3
gene · KG edge: associated_with
PPP1R7 — SDS22 (Protein Phosphatase 1 Regulatory Subuni
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PPP1R7 associated_with COX15
ABCB1 associated_with COX15
PEX3 associated_with COX15
VPS33A associated_with COX15
VPS16 associated_with COX15
COX15 associated_with RPL4
COX15 co_expressed_with COX4I1
COX15 co_expressed_with COX7A1
Chronic Tendon Injury downregulates COX15
COX15 inhibits COX4I1

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