Contents

DLG2 Gene

🧬 Gene Info

Gene Symbol	DLG2
Chromosome	11q14.1
Protein Type	Scaffold Protein
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the postsynaptic density of excitatory synapses
Pathways	PI3K, MAPK signaling
UniProt ID	Q9UQB8
NCBI Gene ID	1749
Ensembl ID	ENSG00000150672
GeneCards	DLG2
Human Protein Atlas	DLG2
SH3 domain	Binds to proline-rich motifs in proteins like AKAP5
Guanylate kinase (GK) domain	Associates with GKAP/SAPAP proteins, linking to Homer and Shank complexes
Associated Diseases	neurodegeneration
Interactions	APOE, APP, BIN1, NR3C2, PICALM, PTK2B
KG Connections	34 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph