| Gene Symbol | DLG2 |
| Chromosome | 11q14.1 |
| Protein Type | Scaffold Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the postsynaptic density of excitatory synapses |
| Pathways | PI3K, MAPK signaling |
| UniProt ID | Q9UQB8 |
| NCBI Gene ID | 1749 |
| Ensembl ID | ENSG00000150672 |
| GeneCards | DLG2 |
| Human Protein Atlas | DLG2 |
| SH3 domain | Binds to proline-rich motifs in proteins like AKAP5 |
| Guanylate kinase (GK) domain | Associates with GKAP/SAPAP proteins, linking to Homer and Shank complexes |
| Associated Diseases | neurodegeneration |
| Interactions | APOE, APP, BIN1, NR3C2, PICALM, PTK2B |
| KG Connections | 33 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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