PTK2B

Understanding Entity Pages

This page aggregates everything SciDEX knows about PTK2B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PTK2B is a gene implicated in neurodegeneration research. Key relationships include: contributes to, activates, associated with. Associated with ALS, Als, Leukemia. Connected to 39 entities in the SciDEX knowledge graph.

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graph TD
    PTK2B["<b>PTK2B</b>"]
    Leukemia{"Leukemia"}
    PTK2B -->|"activates"| Leukemia
    Als{"Als"}
    PTK2B -->|"activates"| Als
    PTK2B -->|"interacts with"| Als
    ALS{"ALS"}
    PTK2B -->|"activates"| ALS
    IL7R["IL7R"]
    PTK2B -->|"contributes to"| IL7R
    JAK2["JAK2"]
    PTK2B -->|"contributes to"| JAK2
    PDGFRB["PDGFRB"]
    PTK2B -->|"contributes to"| PDGFRB
    ETV6["ETV6"]
    PTK2B -->|"activates"| ETV6
    NTRK3["NTRK3"]
    PTK2B -->|"contributes to"| NTRK3
    CSF1R["CSF1R"]
    PTK2B -->|"contributes to"| CSF1R
    ABL1["ABL1"]
    PTK2B -->|"contributes to"| ABL1
    GENES["GENES"]
    PTK2B -->|"activates"| GENES
    TYK2["TYK2"]
    TYK2 -->|"contributes to"| PTK2B
    ABL2["ABL2"]
    ABL2 -->|"contributes to"| PTK2B
    NTRK3 -->|"contributes to"| PTK2B
    ABL1 -->|"contributes to"| PTK2B
    PIK3CA["PIK3CA"]
    PIK3CA -->|"associated with"| PTK2B
    CSF1R -->|"contributes to"| PTK2B
    EPOR["EPOR"]
    EPOR -->|"contributes to"| PTK2B
    TSLP["TSLP"]
    TSLP -->|"contributes to"| PTK2B
    GENES -->|"activates"| PTK2B
    JAK2 -->|"contributes to"| PTK2B
    style PTK2B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0