gene 726 words KG: DOCK3 2026-03-20
kind:genesection:genesstate:published
Contents

DOCK3 - Dedicator of Cytokinesis 3

🧬 Gene Info
Gene SymbolDOCK3
Full NameDedicator of Cytokinesis 3
AliasesPage for DOCK3, Page for DOCK3 Protein
Chromosome3p21.2
FunctionRac1 Activation: DOCK3 activates Rac1, a key regulator of actin cytoskeleton dynamics [2]
Primary ExpressionCerebral cortex, Hippocampus, Motor neurons, Spinal cord
Molecular Weight220 kDa
PathwaysPI3K, PI3K signaling, Wnt Signaling
UniProt IDQ9UPJ4
NCBI Gene ID1786
Ensembl IDENSG00000157617
OMIM607337
GeneCardsDOCK3
Human Protein AtlasDOCK3
Symbol [@miyamoto2017] DOCK3 [@qian2019] [@watabe2016] Full NameDedicator of Cytokinesis 3
Associated DiseasesAmyotrophic Lateral Sclerosis, Parkinson's Disease, Neurodegeneration
InteractionsSIRT3, ERBB4, APP, NF-ΚB, INFLAMMATION, NEUROINFLAMMATION
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph