ERBB4

Understanding Entity Pages

This page aggregates everything SciDEX knows about ERBB4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ERBB4 is a gene implicated in neurodegeneration research. Key relationships include: activates, inhibits, regulates. Associated with Aging, Als, Alzheimer. Connected to 74 entities in the SciDEX knowledge graph.

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graph TD
    ERBB4["<b>ERBB4</b>"]
    Alzheimer{"Alzheimer"}
    ERBB4 -->|"inhibits"| Alzheimer
    ERBB4 -->|"activates"| Alzheimer
    Aging{"Aging"}
    ERBB4 -->|"activates"| Aging
    Depression{"Depression"}
    ERBB4 -->|"activates"| Depression
    Cardiovascular{"Cardiovascular"}
    ERBB4 -->|"activates"| Cardiovascular
    Epilepsy{"Epilepsy"}
    ERBB4 -->|"activates"| Epilepsy
    Schizophrenia{"Schizophrenia"}
    ERBB4 -->|"activates"| Schizophrenia
    Ms{"Ms"}
    ERBB4 -->|"activates"| Ms
    Als{"Als"}
    ERBB4 -->|"inhibits"| Als
    Anxiety{"Anxiety"}
    ERBB4 -->|"inhibits"| Anxiety
    ERBB4 -->|"inhibits"| Schizophrenia
    ERBB4 -->|"inhibits"| Ms
    NRG1["NRG1"]
    NRG1 -->|"contributes to"| ERBB4
    NRG1 -->|"activates"| ERBB4
    DISC1["DISC1"]
    DISC1 -->|"inhibits"| ERBB4
    MIRNAS["MIRNAS"]
    MIRNAS -->|"regulates"| ERBB4
    RELN["RELN"]
    RELN -->|"regulates"| ERBB4
    MYC["MYC"]
    MYC -->|"regulates"| ERBB4
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"activates"| ERBB4
    DISC1 -->|"associated with"| ERBB4
    NRG1 -->|"associated with"| ERBB4
    AMYLOID["AMYLOID"]
    AMYLOID -->|"inhibits"| ERBB4
    ALZHEIMER_S_DISEASE -->|"inhibits"| ERBB4
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"inhibits"| ERBB4
    style ERBB4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0