gene 1,338 words KG: DYRK1B 2026-03-24
kind:genesection:genesstate:published
Contents

DYRK1B — Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B

🧬 Gene Info
Gene SymbolDYRK1B
Full NameDual Specificity Tyrosine Phosphorylation Regulated Kinase 1B
AliasesDual-specificity Tyrosine-Phosphorylation Regulated Kinase 1B
Chromosome19p13.12
Protein TypeKinase
Functionencodes a dual-specificity protein kinase belonging to the DYRK family, which phosphorylates substrates on both serine/threonine and tyrosine residues.
Primary Expressionthe brain and is catalytically active at the time of translation through an intramolecular autophosphorylation mechanism
Molecular Weight64.7 kDa
Amino Acids629 aa
Exons15
PathwaysMitochondrial Function
UniProt IDQ9Y463
NCBI Gene ID9149
Ensembl IDENSG00000105204
OMIM604556
GeneCardsDYRK1B
Human Protein AtlasDYRK1B
Associated Diseasesneurodegeneration
InteractionsSTAT3, DYRK1A, MITOCHONDRIAL DYSFUNCTION, ATP, CRBN
KG Connections17 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph