| Gene Symbol | SHH |
| Full Name | Sonic Hedgehog |
| Chromosome | 7q36.3 |
| Function | is a pivotal signaling molecule that plays fundamental roles in embryonic development, tissue patterning, and adult tissue homeostasis. |
| Primary Expression | Substantia nigra, Cerebellum, Cortex, Hippocampus, Developing brain, Adult neural stem cells |
| Molecular Weight | 19 kDa |
| Amino Acids | 462 aa |
| Pathways | Differentiation, Hedgehog, Sonic Hedgehog, Wnt |
| UniProt ID | Q15465 |
| NCBI Gene ID | 6469 |
| Ensembl ID | ENSG00000164690 |
| OMIM | 600725 |
| GeneCards | SHH |
| Human Protein Atlas | SHH |
| Protein Size | 462 amino acids (pre-proprotein), 19 kDa mature ligand |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Cancer |
| Interactions | GBM, MAOA, GFRAL, ADCY3, AKT, GLI1 |
| KG Connections | 228 knowledge graph edges |
| Databases | GeneCardsHPASTRING |