gene 2,474 words KG: EPHA10 2026-03-25
kind:genesection:genesstate:published
Contents

EPHA10 Gene

🧬 Gene Info
Gene SymbolEPHA10
Full NameEphrin Type-A Receptor 10
Chromosome4q13.3
Protein TypeReceptor
FunctionSperm Function: EPHA10 is highly expressed in testis and is involved in sperm motility and male fertility[@matsuura2012].
Primary ExpressionTestis (high), Brain (low), Immune cells (moderate)
Molecular Weight105 kDa
Amino Acids954 aa
Exons17
PathwaysEpigenetic, Oxidative Stress
UniProt IDQ8IWU6
NCBI Gene ID284656
Ensembl IDENSG00000116675
OMIM612663
GeneCardsEPHA10
Human Protein AtlasEPHA10
Associated DiseasesCancer, limited brain involvement
InteractionsEGF, SMAD1, AXON, GENES, NEUROINFLAMMATION, OXIDATIVE STRESS
KG Connections17 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.47

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

SMAD1 Gene
gene · KG edge: activates
EGF Gene
gene · KG edge: activates
Genes
index · KG edge: activates
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (12 edges)

EPHA10 activates EGF
EPHA10 activates SMAD1
EPHA10 activates Neuroinflammation
EPHA10 activates Oxidative Stress
EPHA10 activates Epigenetic
EPHA10 activates Inflammation
EPHA10 activates AXON
SMAD1 activates EPHA10
EGF activates EPHA10
PIF upregulates EPHA10