gene 1,699 words KG: IFNAR2 2026-03-28
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:neuroinflammation
Contents

IFNAR2 — Interferon Alpha Receptor 2

🧬 Gene Info
Gene SymbolIFNAR2
Full NameInterferon Alpha and Beta Receptor Subunit 2
Chromosome21q22.1
Primary Expressionneurons, microglia, astrocytes, and [oligodendrocytes](/entiti
Amino Acids505 aa
PathwaysJAK-STAT signaling
UniProt ID[P48551](https://www.uniprot.org/uniprot/P48551)
NCBI Gene ID3455
Ensembl IDENSG00000159197
OMIM206550
GeneCardsIFNAR2
Human Protein AtlasIFNAR2
RefSeqNM_001034200
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsC1Q, PSEN1, STAT2, VIRAL INFECTIONS, ALZHEIMER
KG Connections36 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (3)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.43

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (10)

Alzheimer Indonesia
institution · KG edge: regulates
STAT2 Gene - Signal Transducer and Activator of Transcr
gene · KG edge: expressed_in
C1QA Gene — Complement Component 1q A Chain
gene · KG edge: regulates
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: regulates
TNF (Redirect)
redirect · KG edge: regulates

Knowledge Graph (12 edges)

IFNAR2 regulates C1Q
IFNAR2 regulates TNF
IFNAR2 expressed_in STAT2
IFNAR2 regulates PSEN1
IFNAR2 regulates Rb
IFNAR2 expressed_in PSEN
IFNAR2 implicated_in TBK1
IFNAR2 regulates ASTROCYTE
IFNAR2 regulates ALZHEIMER
IFNAR2 regulates ASTROCYTES