Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VIRAL INFECTIONS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
VIRAL INFECTIONS is a concept in neurodegeneration research. Key relationships include: activates, associated with, therapeutic target. Associated with ALS, Aging, Als. Connected to 339 entities in the SciDEX knowledge graph.
| Name | VIRAL INFECTIONS |
| Key Genes/Proteins | INFLAMMATION |
| Related Diseases | Inflammation, Infection, Viral Infection, Als, Autoimmune |
Knowledge base pages for this entity
graph TD
VIRAL_INFECTIONS["VIRAL INFECTIONS"]
VIRAL_INFECTIONS -->|"causes"| INFLAMMATION["INFLAMMATION"]
VIRAL_INFECTIONS -->|"target for"| Fibrosis["Fibrosis"]
VIRAL_INFECTIONS -->|"target for"| Ms["Ms"]
VIRAL_INFECTIONS -->|"target for"| Als["Als"]
VIRAL_INFECTIONS -->|"activates"| Inflammation["Inflammation"]
VIRAL_INFECTIONS -->|"activates"| Cancer["Cancer"]
VIRAL_INFECTIONS -->|"regulates"| Tumor["Tumor"]
AGING["AGING"] -->|"target for"| VIRAL_INFECTIONS
DRP1["DRP1"] -->|"target for"| VIRAL_INFECTIONS
APOPTOSIS["APOPTOSIS"] -.biomarker for.-> VIRAL_INFECTIONS
DNA["DNA"] -.biomarker for.-> VIRAL_INFECTIONS
ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -.biomarker for.-> VIRAL_INFECTIONS
ALZHEIMER["ALZHEIMER"] -.biomarker for.-> VIRAL_INFECTIONS
CD4["CD4"] -->|"activates"| VIRAL_INFECTIONS
CD8["CD8"] -->|"activates"| VIRAL_INFECTIONS
MAF["MAF"] -->|"inhibits"| VIRAL_INFECTIONS
CANCER["CANCER"] -->|"activates"| VIRAL_INFECTIONS| Target | Relation | Type | Str |
|---|---|---|---|
| Inflammation | activates | disease | 1.00 |
| Infection | associated_with | disease | 1.00 |
| Viral Infection | associated_with | disease | 1.00 |
| INFLAMMATION | causes | gene | 0.95 |
| Als | activates | disease | 0.95 |
| Infection | activates | disease | 0.95 |
| Viral Infection | activates | disease | 0.95 |
| Infection | therapeutic_target | disease | 0.95 |
| Viral Infection | therapeutic_target | disease | 0.95 |
| Autoimmune | activates | disease | 0.85 |
| Cancer | therapeutic_target | disease | 0.85 |
| Cancer | associated_with | disease | 0.85 |
| Inflammation | associated_with | disease | 0.85 |
| Alzheimer | associated_with | disease | 0.85 |
| Parkinson | associated_with | disease | 0.85 |
| Infection | causes | disease | 0.85 |
| Viral Infection | causes | disease | 0.85 |
| Immune Response | activates | pathway | 0.80 |
| Cancer | activates | disease | 0.75 |
| Als | associated_with | disease | 0.75 |
| Inflammation | interacts_with | disease | 0.75 |
| Cardiovascular | associated_with | disease | 0.75 |
| Neurodegeneration | activates | disease | 0.75 |
| Aging | causes | disease | 0.75 |
| Amyotrophic Lateral Sclerosis | associated_with | disease | 0.75 |
| Parkinson | implicated_in | disease | 0.75 |
| Als | implicated_in | disease | 0.75 |
| Als | causes | disease | 0.75 |
| Inflammation | causes | disease | 0.75 |
| Infection | implicated_in | disease | 0.75 |
| Viral Infection | implicated_in | disease | 0.75 |
| CYTOKINES | regulates | gene | 0.70 |
| CANCER | activates | gene | 0.70 |
| Immune Response | regulates | pathway | 0.70 |
| Inflammasome | activates | pathway | 0.70 |
| INFLAMMATION | associated_with | gene | 0.70 |
| CANCER | associated_with | gene | 0.70 |
| AMYOTROPHIC LATERAL SCLEROSIS | associated_with | gene | 0.70 |
| Immune Response | causes | pathway | 0.70 |
| Oxidative Stress | causes | pathway | 0.70 |
| Apoptosis | activates | pathway | 0.70 |
| Immune Response | associated_with | pathway | 0.70 |
| MITOCHONDRIA | activates | gene | 0.70 |
| Fibrosis | therapeutic_target | disease | 0.65 |
| Ms | therapeutic_target | disease | 0.65 |
| Als | therapeutic_target | disease | 0.65 |
| Ms | activates | disease | 0.65 |
| Ms | regulates | disease | 0.65 |
| Tumor | regulates | disease | 0.65 |
| Autoimmune | regulates | disease | 0.65 |
| Source | Relation | Type | Str |
|---|---|---|---|
| INFLAMMATION | activates | gene | 0.90 |
| ALZHEIMER | associated_with | gene | 0.80 |
| PARKINSON | associated_with | gene | 0.80 |
| NEURODEGENERATION | activates | gene | 0.70 |
| OXIDATIVE STRESS | causes | gene | 0.70 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.70 |
| PARKINSON'S DISEASE | associated_with | gene | 0.70 |
| PARKINSON'S DISEASE | implicated_in | gene | 0.70 |
| PARKINSON | implicated_in | gene | 0.70 |
| APOPTOSIS | activates | gene | 0.70 |
| INFLAMMATION | interacts_with | gene | 0.70 |
| CANCER | therapeutic_target | gene | 0.70 |
| AGING | therapeutic_target | gene | 0.60 |
| DRP1 | therapeutic_target | gene | 0.60 |
| APOPTOSIS | biomarker_for | gene | 0.60 |
| DNA | biomarker_for | gene | 0.60 |
| ALZHEIMER'S DISEASE | biomarker_for | gene | 0.60 |
| ALZHEIMER | biomarker_for | gene | 0.60 |
| CD4 | activates | gene | 0.60 |
| CD8 | activates | gene | 0.60 |
| MAF | inhibits | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
| GUT-BRAIN AXIS | activates | gene | 0.60 |
| MICROGLIA | activates | gene | 0.60 |
| PARKINSON'S DISEASE | activates | gene | 0.60 |
| PARKINSON | activates | gene | 0.60 |
| CYTOKINES | activates | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | associated_with | gene | 0.60 |
| NEURODEGENERATION | causes | gene | 0.60 |
| AGING | associated_with | gene | 0.60 |
| MICROGLIA ACTIVATION | activates | gene | 0.60 |
| AMYOTROPHIC LATERAL SCLEROSIS | associated_with | gene | 0.60 |
| AGING | causes | gene | 0.60 |
| CYTOKINES | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| CANCER | associated_with | gene | 0.60 |
| NEURODEGENERATION | implicated_in | gene | 0.60 |
| MICROGLIA ACTIVATION | implicated_in | gene | 0.60 |
| CYTOKINES | implicated_in | gene | 0.60 |
| INFLAMMATION | implicated_in | gene | 0.60 |
| EPAS1 | activates | gene | 0.60 |
| BCL2 | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| NEURODEGENERATION | treats | gene | 0.60 |
| PARKINSON'S DISEASE | treats | gene | 0.60 |
| PARKINSON | treats | gene | 0.60 |
| INFLAMMATION | causes | gene | 0.60 |
| BRAIN INFLAMMATION | causes | gene | 0.60 |
| YWHAB | associated_with | gene | 0.60 |
| MITOPHAGY | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||