| Gene Symbol | KMT2B |
| Full Name | MLL2 (Mixed-Lineage Leukemia 2) / MLL4 |
| Aliases | lysine methyltransferase 2B |
| Protein Family | SET1/MLL COMPASS Family |
| Protein Type | Transferase |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | brain tissue |
| Subcellular Localization | Nucleus |
| Molecular Weight | 445 kDa |
| Pathways | FMN-induced Anti-inflammatory Effect |
| UniProt ID | Q9UMN6 |
| GeneCards | KMT2B |
| Human Protein Atlas | KMT2B |
| Alzheimer's Disease | Altered expression and function contributes to epigenetic dysregulation of neuronal survival genes |
| Parkinson's Disease | May affect dopaminergic neuron survival through transcriptional mechanisms |
| Associated Diseases | ALS, Alzheimer |
| Interactions | SHANK3, KMT2D, CACNA1G, KMT2A, SETD1A, NF-ΚB |
| KG Connections | 58 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |